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Olsalazine sodium

Olsalazine sodium structure

CAS No:
6054-98-4
Formula:
C14H10N2O6.2Na
Chemical Name:
Olsalazine sodium
Synonyms:
Benzoic acid,3,3′-(1,2-diazenediyl)bis[6-hydroxy-,sodium salt (1:2);C.I. Mordant Yellow 5,disodium salt;Benzoic acid,3,3′-azobis[6-hydroxy-,disodium salt;C.I. Mordant Yellow 5;C.I. 14130;Acid Chrome Flavine R;Alizarol Flavine A;Chromaven Yellow FA;Chrome Fast Flavine A;Chrome Fast Flavine J;Chrome Yellow A extra;Curolite Yellow 3R;Diamond Chrome Yellow A ex;Eriochromal Flavine A;Eriochrome Flavine A;Fenakrom Yellow 3G;Metachrome Yellow A extra;Monochrome Yellow A ex;Nutrachrome Yellow NYA;Omega Chrome Aurine GL;Pontachrome Flavine A;Salicine Chrome Yellow A Extra;Solochrome Flavine G;Synchromate Flavine A;Telon Chrome Yellow T;Tertrochrome Yellow A;Disodium 3,3′-azobis(6-hydroxybenzoate);Mordant Yellow 5;Azodisal sodium;Ph CJ 91B;Olsalazine sodium;Dipentum;3,3′-Azobis[6-hydroxybenzoic acid] disodium salt;Chrome Yellow AS;Sodium azodisalicylate;Disodium azodisalicylate;Olsalazine disodium
Categories:
Active Pharmaceutical Ingredients > Digestive System Drugs

Description

Olsalazine is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease and Ulcerative Colitis.Target: AntibacterialOlsalazine is a derivative of salicylic acid. Inactive by itself (it is a prodrug), it is converted by the bacteria in the colon to mesalamine. Olsalazine is potent inhibitors of human intestinal macrophages chemotaxis to LTB4 with IC50 of 0.39 mM. Olsalazine (0.4 mM) inhibits the superoxide radical production generated by phorbol myristate acetate (PMA)

Olsalazine sodium Basic Attributes

Molecular Weight：

346.2

Exact Mass：

346.017761

EC Number：

227-975-7

HScode：

2928000090

Characteristics

PSA：

145

Melting Point：

240 °C

Boiling Point：

557.9°C at 760 mmHg

Flash Point：

291.2ºC

Storage Conditions：

-20°C Freezer

Olsalazine sodium Use and Manufacturing

Mordant dye for wool.

Drug Function and Efficacy

This product is a prodrug that is metabolized by bacteria containing azoreductase in the large intestine, releasing 5-aminosalicylic acid to exert its effect.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Olsalazine Sodium
Manufacturer	Zhejiang Zhongyi Pharmaceutical Co., Ltd.

Olsalazine Sodium Capsules
Ingredients	The main ingredient of this product is olsalazine sodium, and its chemical name is 3,3-azobis(6-hydroxybenzoic acid) disodium.
Indication	Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Specifications	0.25g
Manufacturer	Tianjin Lisheng Pharmaceutical Co., Ltd.

Olsalazine Sodium

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Registered Holders

MATRIX PHARMACORP PRIVATE LTD

United States
Active
Dottikon Exclusive Synthesis AG

Switzerland
Active
Liaoning Nirvana Pharmaceutical Co., Ltd.

China
Active

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Recommended Suppliers of Olsalazine sodium

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Olsalazine disodium

CAS No.: 6054-98-4

Content: 99.00%

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