5-(2-Nitroethenyl)-1,3-benzodioxole
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5-(2-Nitroethenyl)-1,3-benzodioxole
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CAS No:
1485-00-3
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Formula:
C9H7NO4
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Chemical Name:
5-(2-Nitroethenyl)-1,3-benzodioxole
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Synonyms:
1,3-Benzodioxole,5-(2-nitroethenyl)-;Styrene,3,4-(methylenedioxy)-β-nitro-;5-(2-Nitroethenyl)-1,3-benzodioxole;1-(2-Nitrovinyl)-3,4-methylenedioxybenzene;3,4-Methylenedioxy-1-(2-nitrovinyl)benzene;5-(2-Nitrovinyl)-1,3-benzodioxole;3,4-(Methylenedioxy)-β-nitrostyrene;5-(2-Nitrovinyl)benzodioxole;NSC 10120;NSC 105303;NSC 170724;MNS;Syk inhibitor III
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CAS No:
Characteristics
64.3
2.27
1.4058 (rough estimate)
162.0-163 °C
329.36°C (rough estimate)
168.8±21.3 °C
1.5200 (estimate)
Store at +4°C
Safety Information
UN28116.1/PG3
36/37/38-22-25
36/37/39-26-45
WL5270000
Xn,Xi,T
P261, P264, P270, P271, P280, P301+P310, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, P501
H301
5-(2-Nitroethenyl)-1,3-benzodioxole Use and Manufacturing
Selective inhibitor of Src and Syk tyrosine kinases. Displays antiaggregative activity via inhibition of GPIIb/IIIa activation (IC 50 = 12.7 μ M for thrombin-induced platelet aggregation). Exhibits no effects on Ca 2+ -dependent enzymes, PKC or arachidonic acid metabolism.
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5-(2-Nitroethenyl)-1,3-benzodioxole
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