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Aflatoxins

Aflatoxins structure

CAS No:
1402-68-2
Chemical Name:
Aflatoxins
Synonyms:
Aflatoxins;Flavatoxins;Aflatoxin;Toxins,afla

Description

The aflatoxins are a group of molds produced by the fungus Aspergillus flavus. They are natural contaminants of fruits, vegetables, and grains. They are also described as a series of condensed ring heterocyclic compounds. They form colorless to pale yellow crystals. Practically insoluble in water.

Aflatoxins Basic Attributes

Molecular Weight：

1285.13

Exact Mass：

328.05800

EC Number：

214-615-9

Characteristics

PSA：

80.3

XLogP3：

0.50 (est)

Appearance：

Solid

Density：

1.59g/cm3

Melting Point：

257 - 259 °C

Boiling Point：

612.1ºC at 760mmHg

Flash Point：

274.2ºC

Refractive Index：

1.68

Water Solubility：

In water, 477 mg/L at 25 deg C (est)

Storage Conditions：

Storage site should be as close as practical to lab in which carcinogens are to be used, so that only small quantities required for expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ) that bears appropriate label. An inventory should be kept, showing quantity of carcinogen & date it was acquired Facilities for dispensing should be contiguous to storage area.

Vapor Pressure：

5.86X10-11 mm Hg at 25 deg C (est)

Toxicity：

Oral-Human LDL0: 0.229 mg/kg; Oral-Monkey LD50: 1.75 mg/kg

Flammability characteristics：

Flammable; burning releases irritating fumes

Specific rotation：

Specific optical rotation (chloroform): -556 deg at 25 °C/D

Safety Information

Packing level：

Hazard category：

6.1(a)

Transport codes：

3172

Storage features：

Treasury is ventilated, low temperature and dry; stored separately from food materials

Stability/Shelf Life：

Aflatoxins B1, B2, G1, & G2 in water or chloroform solutions or in solid films were decomposed by UV irridiation.

Precautionary statement(s)：

P201, P202, P260, P264, P270, P281, P301+P310, P307+P311, P308+P313, P314, P321, P330, P405, P501

Hazard Statements：

H300

Toxicity

Toxicity class：

most toxic

Aflatoxins Use and Manufacturing

Aflatoxins are used solely for research purposes. They are naturally occurring contaminants formed by certain fungi on agricultural crops, first discovered in the 1960s (IARC 1976).