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Home > Encyclopedia > Tylosin, (2R,3R)-2,3-dihydroxybutanedioate (salt)

Tylosin, (2R,3R)-2,3-dihydroxybutanedioate (salt)

pharmaceutical raw materials
Tylosin, (2R,3R)-2,3-dihydroxybutanedioate (salt) structure

Tylosin, (2R,3R)-2,3-dihydroxybutanedioate (salt) 

structure
  • CAS No:

    1405-54-5

  • Formula:

    C46H77NO17.xC4H6O6

  • Chemical Name:

    Tylosin, (2R,3R)-2,3-dihydroxybutanedioate (salt)

  • Synonyms:

    Tylosin,(2R,3R)-2,3-dihydroxybutanedioate (salt);Tylosin,tartrate;Tylosin,[R-(R*,R*)]-2,3-dihydroxybutanedioate (salt);1966152-64-6

  • Categories:

    Active Pharmaceutical Ingredients  >  Antibiotics

Description

Macrolide antibiotic obtained from cultures of Streptomyces fradiae. The drug is effective against many microorganisms in animals but not in humans.

Tylosin, (2R,3R)-2,3-dihydroxybutanedioate (salt) Basic Attributes

1052.16

1051.519897

215-781-5

5P4625C51T

DTXSID3045938

Characteristics

353.73000

1

powder

1.24 g/cm3

128-132 deg C

1116.3ºC at 760 mmHg

628.9ºC

soluble in water.H2O: 50 mg/mL, clear, yellow-green

2-8°C

1.98X10-34 mm Hg at 25 deg C (est)

Safety Information

3

42/43

22-36/37-45-24/25

YP0875000

Xn

Stable under recommended storage conditions.

P261, P264, P272, P273, P280, P285, P302+P352, P304+P341, P305+P351+P338, P321, P333+P313, P337+P313, P342+P311, P363, P391, P501

H317

|Danger|H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]|P261, P272, P280, P285, P302+P352, P304+P341, P321, P333+P313, P342+P311, P363, and P501|Aggregated GHS information provided by 92 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|P261, P264, P272, P280, P285, P302+P352, P304+P341, P305+P351+P338, P321, P333+P313, P337+P313, P342+P311, P363, and P501|Aggregated GHS information provided by 65 companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)

Fradizine

Tylosin, (2R,3R)-2,3-dihydroxybutanedioate (salt) Use and Manufacturing

Uses

An antibiotic with a large macrocyclic lactone ring.

Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients

Computed Properties

Molecular Weight:1066.2
Hydrogen Bond Donor Count:9
Hydrogen Bond Acceptor Count:24
Rotatable Bond Count:16
Exact Mass:1065.53558789
Monoisotopic Mass:1065.53558789
Topological Polar Surface Area:354
Heavy Atom Count:74
Complexity:1700
Defined Atom Stereocenter Count:23
Defined Bond Stereocenter Count:2
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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