3-Bromo-1,2-diaminobenzene
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3-Bromo-1,2-diaminobenzene
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CAS No:
1575-36-6
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Formula:
C6H7BrN2
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Chemical Name:
3-Bromo-1,2-diaminobenzene
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Synonyms:
3-broMobenzene-1;2-AMino-3-broMoaniline;3-Bromobenzene-1,2-diamine;1,2-Diamino-3-bromobenzene;3-BroMo-o-phenylenediaMine;1,2-BenzenediaMine,3-broMo-;3-Bromophenylene-1,2-diamine;3-Bromobenzene-1,2-diamine97%;3-Bromophenylene-1,2-diamine,1-Bromo-2,3-diaminobenzene
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CAS No:
Characteristics
52
1.3
1.697±0.06 g/cm3(Predicted)
125-126 °C
127-128 °C
129.5±21.8 °C
1.696
Room temperature.
0.002mmHg at 25°C
Safety Information
36/37
P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, P501
H302
|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 2 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
3-Bromo-1,2-diaminobenzene Use and Manufacturing
2000mL 1-neck flask (one neck flask) for 4-bromo-benzo [c] [1, 2, 5] thiadiazole (10g, 46.5 mmol), NaBH4 (17.6g, 465 mmol) were placed into a 900mL EtOH after stirring at room temperature for 16 hours. When the reaction is complete, remove the solvents by rotary evaporation the drier and extracted with CHCl3. Thus extracted organic layer was washed with brine solution. Thereafter, the dried organic layer was again put on MgSO4 and the solvent removed by evaporation dryer to give the title compound C-2-1 (8.0g, 47.6 mmol, 92percent).
3-Bromo-1,2-diaminobenzene is used in the preparation of isomeric bromo analogues of Benzo-1H-triazole as potential inhibitors of protein kinases.
Computed Properties
Molecular Weight:187.04
XLogP3:1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Exact Mass:185.97926
Monoisotopic Mass:185.97926
Topological Polar Surface Area:52
Heavy Atom Count:9
Complexity:97.1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
