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Home > Encyclopedia > 2,2′-Dipyridyl disulfide

2,2′-Dipyridyl disulfide

pharmaceutical raw materials
2,2′-Dipyridyl disulfide structure

2,2′-Dipyridyl disulfide 

structure
  • CAS No:

    2127-03-9

  • Formula:

    C10H8N2S2

  • Chemical Name:

    2,2′-Dipyridyl disulfide

  • Synonyms:

    Pyridine,2,2′-dithiobis-;Pyridine,2,2′-dithiodi-;2,2′-Dithiobis[pyridine];2,2′-Dithiodipyridine;2,2′-Dipyridyl disulfide;Bis(2-pyridyl) disulfide;Di-2-pyridyl disulfide;Bis(2-pyridinyl) disulfide;2-Pyridyl disulfide;Aldrithiol 2;2,2′-Dipyridinyl disulfide;NSC 677438;2-Aldrithiol;NSC 94055;Bis(pyridin-2-yl) disulfide;1,2-Bis(2-pyridinyl) disulfide;2,2′-Bipyridyl disulfide;2′-Aldrithiol;Di-2-pyridinyl disulfide;2,2′-Disulfanediyldipyridine;1,2-Di(pyridin-2-yl)disulfane;2,2-Dithiobispyridine;2-(Pyridin-2-yldisulfanyl)pyridine;219143-69-8;1623131-06-5

  • Categories:

    Pharmaceutical Intermediates  >  Heterocyclic Compound

Description

white to yellowish crystalline powder


Aldrithiol is a member of the class of pyridines that is pyridine which is substituted by a pyridin-2-yldisulfanediyl group at position 2. It is a reagent used in molecular biology as an oxidizing agent. Also used in peptide synthesis and for detecting thiols. It has a role as an oxidising agent. It is an organic disulfide and a member of pyridines.

2,2′-Dipyridyl disulfide Basic Attributes

220.31

220.31

154629

218-343-1

L6X912UPBU

677438|94055

DTXSID70175517

29333990

Characteristics

76.4

2.6

Clear colorless to yellow to tan powder

1.3±0.1 g/cm3

51-52 °C

356.1±17.0 °C at 760 mmHg

210 °C

1.694

H2O: 5 g/L (20 ºC);methanol: soluble 50mg/mL, clear to very slightly hazy, colorless to faintly brownish-yellow

2-8°C

6.14E-05mmHg at 25°C

Safety Information

UN 3335

3

36/37/38-37-20/22

36/37/39-37/39-25-22-36-26

Xi,Xn

Irritant

P261-P305 + P351 + P338

H315-H319-H335

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 65 companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

Electron-accepting molecules in chemical reactions in which electrons are transferred from one molecule to another (OXIDATION-REDUCTION). (See all compounds classified as Oxidants.)

2,2'-dipyridyl disulfide

2,2′-Dipyridyl disulfide Use and Manufacturing

Uses

Used in the determination of thiol groups in biological materials; used in the lactonization reaction reagent of hydroxy acid and PPh3; sulfinylation reagent

Pyridine, 2,2'-dithiobis-: ACTIVE|PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.

Computed Properties

Molecular Weight:220.3
XLogP3:2.6
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:220.01289061
Monoisotopic Mass:220.01289061
Topological Polar Surface Area:76.4
Heavy Atom Count:14
Complexity:148
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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