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Home > Encyclopedia > 3,3′-Dicarboxy-4,4′-diaminobiphenyl

3,3′-Dicarboxy-4,4′-diaminobiphenyl

3,3′-Dicarboxy-4,4′-diaminobiphenyl structure

3,3′-Dicarboxy-4,4′-diaminobiphenyl 

structure
  • CAS No:

    2130-56-5

  • Formula:

    C14H12N2O4

  • Chemical Name:

    3,3′-Dicarboxy-4,4′-diaminobiphenyl

  • Synonyms:

    [1,1′-Biphenyl]-3,3′-dicarboxylic acid,4,4′-diamino-;3,3′-Biphenyldicarboxylic acid,4,4′-diamino-;4,4′-Diamino[1,1′-biphenyl]-3,3′-dicarboxylic acid;3,3′-Benzidinedicarboxylic acid;5,5′-Bianthranilic acid;4,4′-Diamino-3,3′-biphenyldicarboxylic acid;3,3′-Dicarboxybenzidine;5,5′-Dianthranilic acid;Benzidine-m,m′-dicarboxylic acid;3,3′-Dicarboxy-4,4′-diaminobiphenyl;2-Amino-5-(4-amino-3-carboxyphenyl)benzoic acid;78020-20-9

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

3,3′-Dicarboxy-4,4′-diaminobiphenyl Basic Attributes

272.25600

272.26

218-348-9

PLU8S18T9F

DTXSID4062195

White crystals

2922499990

Characteristics

126.64000

3.07680

1.476g/cm3

300 °C (decomp)

557.7ºC at 760 mmHg

291.1ºC

1.724

>40.8 [ug/mL]

2.83E-13mmHg at 25°C

pic-esc 100 mmol/L MDMIAZ 31,11,79

Toxicity

Processes in which dried dye is handled have the greatest potential for employee exposure during the manufacture or repackaging of benzidine-based dyes. ... During use of benzidine-based dyes, the greatest potential for exposure would be expected to be among dye-weighers who handle dry powders. /Benzidine-based dyes/

Drug Information

Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if needed. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Cover skin burns with dry sterile dressings after decontamination ... . /Poison A and B/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in respiratory arrest. Positive pressure ventilation techniques with a bag valve mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start an IV with D5W /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Poison A and B/

3,3′-Dicarboxy-4,4′-diaminobiphenyl Use and Manufacturing

Methods of Manufacturing

By boiling meta-nitrobenzaldehyde with caustic soda, reducing with zinc dust and acidifying.

Uses

Dyestuff|Used for the manufacture of azo dyes containing copper

[1,1'-Biphenyl]-3,3'-dicarboxylic acid, 4,4'-diamino-: INACTIVE

Computed Properties

Molecular Weight:272.26
XLogP3:2.3
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:272.07970687
Monoisotopic Mass:272.07970687
Topological Polar Surface Area:127
Heavy Atom Count:20
Complexity:351
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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