 Home > Encyclopedia > Boc-O-benzyl-L-tyrosine

Boc-O-benzyl-L-tyrosine

Boc-O-benzyl-L-tyrosine structure

CAS No:
2130-96-3
Formula:
C21H25NO5
Chemical Name:
Boc-O-benzyl-L-tyrosine
Synonyms:
BOC-O-BENZYL-L-TYROSINE;BOC-O-BENZYL-L-TYR;BOC-L-TYR(BZL)-OH;BOC-(S)-2-AMINO-3-(4'-BENZYLOXYPHENYL)PROPANOIC ACID;BOC-TYROSINE(BZL)-OH;T-BUTYLOXYCARBONYL-O-BENZYL-L-TYROSINE;N-BOC-O-BENZYL-L-TYROSINE;N-ALPHA-TERT-BUTYLOXYCARBONYL-O-BENZYL-L-TYROSINE
Categories:
Pharmaceutical Intermediates > Antineoplastics

Request for Quotation

Description

Light yellow powder

Boc-O-benzyl-L-tyrosine Basic Attributes

Molecular Weight：

371.43

Exact Mass：

371.43

BRN：

2227416

EC Number：

218-349-4

DSSTox ID：

DTXSID20175567

Color/Form：

White

HScode：

29242990

Characteristics

PSA：

84.9

XLogP3：

3.3

Appearance：

White Powder or Crystalline Powder

Density：

1.185±0.06 g/cm3(Predicted)

Melting Point：

110-112 °C

Boiling Point：

552.4±50.0 °C(Predicted)

Flash Point：

287.9±30.1 °C

Refractive Index：

29.5 ° (C=2, EtOH)

Storage Conditions：

2-8°C

Vapor Pressure：

4.87E-13mmHg at 25°C

Specific rotation：

27 º (c=2% in ethanol)

PKA：

2.99±0.10(Predicted)

Critical Temperature & Pressure：

Store below +30°C.

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

safety instructions：

22-24/25

Precautionary statement(s)：

P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, P501

Hazard Statements：

H302

GHS Classification：

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Boc-O-benzyl-L-tyrosine Use and Manufacturing

Methods of Manufacturing

Suspend O-benzyl-L-tyrosine in dioxane solution, acylate with tert-butoxycarbonyl azide to obtain crude product, extract with ethyl acetate under the condition of pH 9-10 , And then refined by recrystallization.

Uses

Used for peptide synthesis and as amino acid protection monomer.

Boc-Tyr(Bzl)-OH, is an amino acid building block used in peptide synthesis. With a growing peptide drug market the fast, reliable synthesis of peptides is of great importance.

Computed Properties

Molecular Weight:371.4
XLogP3:3.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:371.17327290
Monoisotopic Mass:371.17327290
Topological Polar Surface Area:84.9
Heavy Atom Count:27
Complexity:474
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Benzyl chloride

Ethyl acetate

Recommended Suppliers of Boc-O-benzyl-L-tyrosine

Hangzhou Go Top Peptide Biotech Co.,Ltd. Contact Supplier

CN
6 YRS

Business licensed Certified factory

Manufactory Supplier of Pharmaceutical Peptide,Cosmetic peptide,Custom peptides,API polypeptide,Amino acids and derivatives

H-Phenylglycinol

CAS No.: 2130-96-3

Grade: Research and Industrial Grade

Content: 98.00%

Inquiry
LEADER BIOCHEMICAL GROUP Contact Supplier

CN
8 YRS

Business licensed Certified factory

Manufactory Supplier of Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients,Natural Plant Ingredients,APIS Intermidiates,Daily Chemicals,Agricultural Chemicals,Surfactant Chemicals,Ultraviolet Absorbents,Antioxidant Ingredients,Scientific Research Chemical,Flavors and Fragrances Chemicals

China Most Professional Factory Supply High Qulity Boc-O-benzyl-L-tyrosine CAS 2130-96-3

CAS No.: 2130-96-3

Grade: Pharmaceutical Grade

Content: 99%

Inquiry