2,4-Diacetylphloroglucinol
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2,4-Diacetylphloroglucinol
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CAS No:
2161-86-6
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Formula:
C10H10O5
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Chemical Name:
2,4-Diacetylphloroglucinol
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Synonyms:
Ethanone,1,1′-(2,4,6-trihydroxy-1,3-phenylene)bis-;Phloroglucinol,diacetyl-;1,1′-(2,4,6-Trihydroxy-1,3-phenylene)bis[ethanone];2,4-Diacetylphloroglucinol;K2 (pharmaceutical);K2;2,4,6-Trihydroxy-1,3-diacetylbenzene;5-Acetyl-2,4,6-trihydroxyacetophenone;2,4-Diacetyl-1,3,5-benzenetriol;1,3-Diacetyl-2,4,6-trihydroxybenzene;IPO 15474FS;1-(3-Acetyl-2,4,6-trihydroxyphenyl)ethanone;1-(3-Acetyl-2,4,6-trihydroxyphenyl)ethan-1-one;111318-32-2
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CAS No:
Description
Light Pink Solid
2,4-diacetylphloroglucinol is a benzenetriol that is phloroglucinol in which two of the ring hydrogens are replaced by acetyl groups. It has a role as a bacterial metabolite and an antifungal agent. It is a diketone, an aromatic ketone, a methyl ketone and a benzenetriol. It derives from a phloroglucinol. It is a conjugate acid of a 2,4-diacetylphloroglucinol(1-).
Characteristics
94.8
1.20860
1.422g/cm3
154 °C
374.7ºC at 760mmHg
194.6ºC
1.62
-20°C Freezer
3.81E-06mmHg at 25°C
Safety Information
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
H315
|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Drug Information
Purifying or cleansing agents, usually salts of long-chain aliphatic bases or acids, that exert cleansing (oil-dissolving) and antimicrobial effects through a surface action that depends on possessing both hydrophilic and hydrophobic properties. (See all compounds classified as Detergents.)|Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)
2,4-DAPG
2,4-Diacetylphloroglucinol Use and Manufacturing
Diacetylphloroglucinol (DAPG) is a small molecular weight, phenolic metabolite belonging to the phloroglucinol (1,3,5- trihydroxybenzene) family produced by bacteria, including Pseudomonas strains. DAPG exhibits a broad range of biological activities, albeit with mostly low potency. In the search for novel actives, DAPG and related metabolites are important for dereplication to eliminate leads due to high amounts of weakly potent actives. Although weakly active, this family appears to be important in the biocontrol of plant diseases by some Pseudomonas strains.
Computed Properties
Molecular Weight:210.18
XLogP3:1.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:210.05282342
Monoisotopic Mass:210.05282342
Topological Polar Surface Area:94.8
Heavy Atom Count:15
Complexity:249
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
