Lucigenin
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Lucigenin
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CAS No:
2315-97-1
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Formula:
C28H22N2.2NO3
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Chemical Name:
Lucigenin
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Synonyms:
9,9′-Biacridinium,10,10′-dimethyl-,nitrate (1:2);9,9′-Biacridinium,10,10′-dimethyl-,dinitrate;10,10′-Dimethyl-9,9′-biacridinium dinitrate;Lucigenin;Lucigenin nitrate;Lucigenine;N,N′-Dimethyl-9,9′-biacridinium dinitrate;NSC 151912;L 6868;151237-32-0
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CAS No:
Description
Lucigenin(L-6868; NSC-151912) is a chemiluminescent probe used to indicate the presence of endogenously generated superoxide anion radicals in cells.Upon single-electron reduction of Lucigenin by a radical species the subsequent form of Lucigenin presents an amplified chemiluminescence which is measurable and can be correlated to the respective amount of reactive radical species present in the system. This approach can be used to probe the natural generation of these species as well as t
Characteristics
145.52000
6.18360
Yellow powder with orange to brown cast
>330 °C
acetic acid: soluble10mg/mL
Safety Information
III
5.1
1479
3
24/25
|Warning|H272 (100%): May intensify fire; oxidizer [Danger Oxidizing liquids; Oxidizing solids]|P210, P220, P221, P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, P362, P370+P378, and P501|Aggregated GHS information provided by 2 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Drug Information
Compound such as LUMINESCENT PROTEINS that cause or emit light (PHYSICAL LUMINESCENCE). (See all compounds classified as Luminescent Agents.)
10,10'-dimethyl-9,9'-biacridinium
Lucigenin Use and Manufacturing
Chemiluminescent probe for the detection of peroxides in biological systems.
Computed Properties
Molecular Weight:510.5
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:510.15393443
Monoisotopic Mass:510.15393443
Topological Polar Surface Area:134
Heavy Atom Count:38
Complexity:522
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes
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