 Home > Encyclopedia > 4-Chloro-N-methylbenzenemethanamine

4-Chloro-N-methylbenzenemethanamine

4-Chloro-N-methylbenzenemethanamine structure

CAS No:
104-11-0
Formula:
C8H10ClN
Chemical Name:
4-Chloro-N-methylbenzenemethanamine
Synonyms:
Benzenemethanamine,4-chloro-N-methyl-;Benzylamine,p-chloro-N-methyl-;4-Chloro-N-methylbenzenemethanamine;p-Chloro-N-methylbenzylamine;4-Chloro-N-methylbenzylamine;N-Methyl-p-chlorobenzylamine;N-(p-Chlorobenzyl)-N-methylamine;(4-Chlorobenzyl)methylamine;N-Methyl-4-chlorobenzylamine;NSC 39968;N-Methyl-N-(4-chlorobenzyl)amine;N-(4-Chlorobenzyl)-N-methylamine;4-Chlorobenzyl-N-methylamine;1-(4-Chlorophenyl)-N-methylmethanamine;[(4-Chlorophenyl)methyl](methyl)amine
Categories:
Chemical Reagents > Organic Reagents

Request for Quotation

4-Chloro-N-methylbenzenemethanamine Basic Attributes

Molecular Weight：

155.62

Exact Mass：

155.62

EC Number：

203-175-3

DSSTox ID：

DTXSID0059291

HScode：

2921499090

Characteristics

PSA：

XLogP3：

2.2

Density：

1.088±0.06 g/cm3(Predicted)

Boiling Point：

120-123 °C @ Press: 15 Torr

Flash Point：

106.1±0.0 °C

Refractive Index：

1.5380 to 1.5420

Safety Information

Packing level：

Ⅲ

Hazard category：

IRRITANT

Transport codes：

2735

hazard class code：

22-34-52-41-37/38

safety instructions：

23-26-36/37/39-45-39

Marks：

Xi,C,Xn

Precautionary statement(s)：

P260, P261, P264, P270, P271, P280, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P321, P330, P332+P313, P362, P363, P403+P233, P405, P501

Hazard Statements：

H302

GHS Classification：

|Danger|H302 (33.33%): Harmful if swallowed [Warning Acute toxicity, oral]|P260, P261, P264, P270, P271, P280, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P321, P330, P332+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 3 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

4-Chloro-N-methylbenzenemethanamine Use and Manufacturing

Methods of Manufacturing

(4-Chlorobenzyl)methyIamine (30)To a stirred solution of 4-chlorobenzylchloride (3.00 g, 18.63 mmol) in THF (300 ml) under NTo a stirred solution of 4-chlorobenzylchloride (18, 3.00 g, 18.63 mmol) in THF (300 mL) under N(4-Chlorobenzyl)methyIamine (30)To a stirred solution of 4-chlorobenzylchloride (3.00 g, 18.63 mmol) in THF (300 ml) under N2 at 0 0C, was added methylamine solution in water (40% v/v) (9.03 mi, 93.48 mmol) and the reaction allowed to progress at room temperature overnight. The solvent was removed by rotary evaporation with water removed by azeotroping with toluene. The crude product was purified directly by column chromatography using EtOAc (100%) followed by EtOAc: MeOH: NEt3 (92: 5: 3) as eluent to give 30 as a yellow oil (2.49 g, 81%); 1H NMR (CDCi3, 300 MHz) delta 7.25 - 7.18 (4H, m), 3.66 (2H, s), 2.38 (3H, s), 1.65 ( 1H, s); 13C NMR (CDCI3, 100 MHz) delta 138.6 (IV), 132.6 (IV), 129.5 (2C), 128.4 (2C), 55.2, 35.8; HRMS (ESI): Found 156.0580 (M+). C8H10NCI (M+) requires 156.0556.To a stirred solution of 4-chlorobenzylchloride (18, 3.00 g, 18.63 mmol) in THF (300 mL) under N2 at 0 C, was added methylamine solution in water (40% v/v) (9.03 mL, 93.48 mmol) and the reaction allowed to progress at room temperature overnight. The solvent was removed by rotary evaporation with water removed by azeotroping with toluene. The crude product was purified directly by column chromatography using EtOAc (100%) followed by EtOAc:MeOH:NEt3 (92:5:3) as eluent to give 22 as a yellow oil (2.49 g, 81%); 1H NMR (CDCl3, 300 MHz) delta 7.25-7.18 (4H, m, ArH), 3.66 (2H, s, CH2), 2.38 (3H, s, CH3), 1.65 (1H, s, NH); 13C NMR (CDCl3, 100 MHz) delta 138.6 (Arqu), 132.6 (Arqu), 129.5 (2 × ArC-H), 128.4 (2 × ArC-H), 55.2 (CH2), 35.8 (CH3). HRMS (ES): Found 156.0556 (M + H)+: C8H11NCl (M + H)+ requires 156.0575.The

Manufacturing Info：

Benzenemethanamine, 4-chloro-N-methyl-: INACTIVE

Computed Properties

Molecular Weight:155.62
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:155.0501770
Monoisotopic Mass:155.0501770
Topological Polar Surface Area:12
Heavy Atom Count:10
Complexity:87.3
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

SODIUM SULFATE

Sodium sulfate

Recommended Suppliers of 4-Chloro-N-methylbenzenemethanamine

Dayang Chem (Hangzhou) Co.,Ltd Contact Supplier

CN
4 YRS

Business licensed Certified factory

Manufactory Supplier of N-Diethyl-m-toluamide,6-Methyluracil,Anisole,4-Dimethoxybenzoic acid,CS (lacrimator),Daucosterol,N,N-Formylmorpholine,Epichlorohydrin,Tetramethylguanidine,Dimethicone,3

4-Chloro-N-methylbenzylamine

CAS No.: 104-11-0

Grade: Industrial Grade

Content: 98%

Inquiry
Creasyn Finechem(Tianjin) Co., Ltd. Contact Supplier

CN
3 YRS

Business licensed

Trader Supplier of N,N'-Dimethylethylenediamine

4-Chloro-N-methylbenzylamine

CAS No.: 104-11-0

Inquiry
Shandong Ailike New Material Technology Contact Supplier

CN
2 YRS

Business licensed

Trader Supplier of API,Antibiotics,Anti cancer category

(4-CHLORO-BENZYL)-METHYL-AMINE

Unit Price: $10 /KG EXW

CAS No.: 104-11-0

Grade: Industrial Grade

Content: 98%

Inquiry

Latest News on 4-Chloro-N-methylbenzenemethanamine

Preparation and purification of zinc chloride

Learn More Other Chemicals

2-Bromophenacyl bromide, 90%

49851-55-0
1H-Indazol-7-ol

81382-46-9
6-Chloro-4-forMyl-nicotinic acid

1031433-06-3
3-Hydroxy-2,4,5-trifluorobenzoic acid Formula

116751-24-7
2-Methyl-1-heptene Formula

15870-10-7
1-(3,5-Dinitrophenyl)ethanone Formula

14401-75-3
α-Amino-3-bromobenzeneacetic acid Structure

79422-73-4
6-(BROMOMETHYL)-1,3-BENZOTHIAZOLE,97% Structure

499770-85-3
What is Allyl methacrylate

96-05-9
What is ethyl 5-hydroxy-2-Methylnicotinate

60390-47-8

Hot Searches: carbon monoxide formula; cefepine; nitrohydrochloric acid; hexane msds; red88 ag; palm olein

Guide of 4-Chloro-N-methylbenzenemethanamine

Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Computed Properties
Material
Recommended Suppliers
Latest News
Learn More Other Chemicals

4-Chloro-N-methylbenzenemethanamine

SDS

Request for Quotation



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.