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Home > Encyclopedia > (+)-Carvone

(+)-Carvone

(+)-Carvone structure

(+)-Carvone 

structure
  • CAS No:

    2244-16-8

  • Formula:

    C10H14O

  • Chemical Name:

    (+)-Carvone

  • Synonyms:

    2-Cyclohexen-1-one,2-methyl-5-(1-methylethenyl)-,(5S)-;p-Mentha-6,8-dien-2-one,(S)-(+)-;2-Cyclohexen-1-one,2-methyl-5-(1-methylethenyl)-,(S)-;(5S)-2-Methyl-5-(1-methylethenyl)-2-cyclohexen-1-one;(+)-Carvone;d-Carvone;d-1-Methyl-4-isopropenyl-6-cyclohexen-2-one;Carvone,(+)-;(S)-Carvone;(S)-(+)-Carvone;D-(+)-Carvone;D-Carvone;Talent;(S)-(+)-p-Mentha-6,8-dien-2-one;(S)-2-Methyl-5-(1-methylethenyl)-2-cyclohexen-1-one;(S)-2-Methyl-5-(prop-1-en-2-yl)cyclohex-2-en-1-one;(5S)-2-Methyl-5-(prop-1-en-2-yl)cyclohex-2-en-1-one;(S)-2-Methyl-5-(prop-1-en-2-yl)cyclohex-2-enone;53763-73-8

  • Categories:

    Cosmetic Ingredient  >  Perfuming

Description

(S)-(+)-Carvone (D Carvone) is a naturally occuring conmpound found in several food items and can be used in flavouring foods[1].


D-carvone appears as pale yellow or colorless liquid. (NTP, 1992)|Liquid|((+)-form) colourless to light yellow liquid with a caraway-like odour


D-carvone appears as pale yellow or colorless liquid. (NTP, 1992)|(+)-carvone is a carvone having (S) configuration. It is an enantiomer of a (-)-carvone.

(+)-Carvone Basic Attributes

150.22

150.22

2042970

218-827-2

4RWC1CMS3X

2810

DTXSID8020256

29142900

Characteristics

17.1

2.4

Clear colorless to pale yellow Liquid

0.960 g/cm3 @ Temp: 24 °C

<15 °C

231 °C

204 °F

1.481

H2O: <0.1 g/100 mL at 25 ºC

-20°C

0.115 mm Hg at 25 deg C (est)

Oral-rat LD50: 3.71 mg/kg

Thermal decomposition spicy irritating smoke

57 º (c=neat)

May be sensitive to prolonged exposure to light and air. Insoluble in water.

Ketones

D-CARVONE may be sensitive to prolonged exposure to light and air. Incompatible with strong oxidizing agents and strong reducing agents (NTP, 1992)

Safety Information

II

6.1(a)

2810

1

22

24/25

OS8670000

Xi

The warehouse is low-temperature, ventilated and dry; stored separately from food materials

Irritant

Stable. Combustible. Incompatible with strong oxidizing agents, strong reducing agents.

P261, P264, P270, P272, P280, P301+P312, P302+P352, P321, P330, P333+P313, P363, P501

H302

This chemical is combustible. (NTP, 1992)

|Warning|H302 (16.65%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P272, P280, P301+P312, P302+P352, P321, P330, P333+P313, P363, and P501|Aggregated GHS information provided by 1624 companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H317: May cause an allergic skin reaction [Warning Sensitization, Skin]|P261, P272, P280, P302+P352, P321, P333+P313, P363, and P501

Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)

Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]: As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)

SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should protect this chemical from exposure to light. Keep the container tightly closed under an inert atmosphere, and store under refrigerated temperatures. (NTP, 1992)

MINIMUM PROTECTIVE CLOTHING: If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves. RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter). (NTP, 1992)

Toxicity

most toxic

Drug Information

SYMPTOMS: Symptoms of exposure to this compound may include irritation. ACUTE/CHRONIC HAZARDS: This compound is highly toxic by inhalation, ingestion or skin absorption (is readily absorbed). It may cause irritation. When heated to decomposition it emits acrid smoke and toxic fumes of carbon monoxide and carbon dioxide. (NTP, 1992)

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Generally, the induction of vomiting is NOT recommended outside of a physician's care due to the risk of aspirating the chemical into the victim's lungs. However, if the victim is conscious and not convulsing and if medical help is not readily available, consider the risk of inducing vomiting because of the high toxicity of the chemical ingested. Ipecac syrup or salt water may be used in such an emergency. IMMEDIATELY transport the victim to a hospital. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

(+)-Carvone Use and Manufacturing

Methods of Manufacturing

It can be prepared by neutral sulfite method or hydrogen sulfide derivatives from artemisia annua oil or dill oil.

Uses

Used as a synthetic fragrance

2-Cyclohexen-1-one, 2-methyl-5-(1-methylethenyl)-, (5S)-: ACTIVE

Food additives -> Flavoring Agents

Flavoring Agents

Computed Properties

Molecular Weight:150.22
XLogP3:2.4
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:150.104465066
Monoisotopic Mass:150.104465066
Topological Polar Surface Area:17.1
Heavy Atom Count:11
Complexity:223
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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