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Acridine Red

Acridine Red structure

CAS No:
2465-29-4
Formula:
C15H15N2O.Cl
Chemical Name:
Acridine Red
Synonyms:
Xanthylium,3,6-bis(methylamino)-,chloride (1:1);3H-Xanthen-6-amine,N-methyl-3-(methylimino)-,monohydrochloride;Acridine Red 3B;Xanthylium,3,6-bis(methylamino)-,chloride;C.I. 45000;Acridine Red;Acridin Red;98343-14-7;115624-91-4;116496-73-2;92890-47-6;1051370-42-3;1087749-04-9

Description

ChEBI: A hydrochloride obtained by combining the free base of acridine red 3B with one molar equivalent of hydrogen chloride. Used for staining RNA in conjunction with malachite green.

Acridine Red Basic Attributes

Molecular Weight：

274.75

Exact Mass：

274.087280

EC Number：

219-568-8

UNII：

0KGA4B4N1H

NSC Number：

13972|11856

HScode：

2921199090

Characteristics

PSA：

37.53000

XLogP3：

3.98480

Boiling Point：

438.8ºC at 760mmHg

Flash Point：

219.2ºC

Vapor Pressure：

6.68E-08mmHg at 25°C

Flammability characteristics：

Flammable; decomposes by heating to release toxic nitrogen oxides and hydrogen chloride fumes

Experimental Properties：

CATIONIC

Safety Information

Storage features：

Warehouse ventilated, low temperature and dry

GHS Classification：

|Danger|H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]|P261, P272, P280, P285, P302+P352, P304+P341, P321, P333+P313, P342+P311, P363, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Toxicity

Interactions：

T4 PHOTOINACTIVATION WAS OBSERVED AFTER INCUBATION WITH ACRIDINE RED. THE INACTIVATION FOLLOWED SINGLE HIT KINETICS AS A FUNCTION OF THE IRRADIATION TIME.

Drug Information

Absorption：

OF THE 20 DYES TESTED, ALL PREVIOUSLY CLAIMED TO BE ELIMINATED THROUGH THE PANCREAS, ONLY 6 APPEARED IN THE PANCREATIC JUICE OF DOGS. THE INTENSITY OF DYE COLOR IN PANCREATIC JUICE DECREASED IN THE ORDER: BASIC FUCHSINE, ACRIDINE RED, NEW FUCHSINE, RHODAMINE B, PHENOL RED, & RHODAMINE 6G. THE CHLORINE CONTENT WAS RELATED TO AMYLASE OR DYE CONTENT, BUT WAS INVERSELY RELATED TO SECRETED VOLUME.

MeSH Entry Terms：

acridine red

Acridine Red Use and Manufacturing

Methods of Manufacturing

CONDENSATION OF M-DIMETHYLAMINOPHENOL WITH FORMALDEHYDE FOLLOWED BY DEHYDRATION OF THE PRODUCT WITH SULFURIC ACID AND OXIDATION

Uses

BASIC DYE|BIOLOGICAL STAIN

Production

(1979) NOT PRODUCED COMMERCIALLY IN U.S.|(1981) NOT PRODUCED COMMERCIALLY IN U.S.

Manufacturing Info：

Xanthylium, 3,6-bis(methylamino)-, chloride (1:1): INACTIVE|A GROUP OF DYES WHOSE MOLECULAR STRUCTURE IS RELATED TO THAT OF XANTHENE. THE AROMATIC (C6H4) GROUPS CONSTITUTE THE CHROMOPHORE. COLOR INDEX NUMBER RANGES FROM 45000 TO 45999... /XANTHENE DYES/

Computed Properties

Molecular Weight:274.74
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:274.0872908
Monoisotopic Mass:274.0872908
Topological Polar Surface Area:35.2
Heavy Atom Count:19
Complexity:423
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Recommended Suppliers of Acridine Red

HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

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ACRIDINE RED

CAS No.: 2465-29-4

Content: 99.00%

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Guide of Acridine Red

Description
Basic Attributes
Characteristics
Safety Information
Toxicity
Drug Information
Use and Manufacturing
Computed Properties
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