Piposulfan
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Piposulfan
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CAS No:
2608-24-4
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Formula:
C12H22N2O8S2
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Chemical Name:
Piposulfan
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Synonyms:
1-Propanone,1,1′-(1,4-piperazinediyl)bis[3-[(methylsulfonyl)oxy]-;Piperazine,1,4-dihydracryloyl-,dimethanesulfonate (ester);Piperazine,1,4-bis[3-[(methylsulfonyl)oxy]-1-oxopropyl]-;Piperazine,1,4-dihydracryloyl-,dimethanesulfonate;1,1′-(1,4-Piperazinediyl)bis[3-[(methylsulfonyl)oxy]-1-propanone];A-20968;Ancyte;N,N′-Bis(3-methanesulfonyloxypropionyl)piperazine;Piposulfan;NSC-47774
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CAS No:
Description
Piposulfan is a N-acylpiperazine and a methanesulfonate ester.|Piposulfan is an alkyl sulfonate with potential antineoplastic activity. Piposulfan alkylates DNA, thereby producing DNA interstrand crosslinks and DNA strand breaks and inhibiting DNA replication. This agent has been shown to exhibit antitumor activity in an animal model of prostate cancer. (NCI04)
Characteristics
144
0.42720
1.421g/cm3
175-177 °C
713.1ºC at 760mmHg
385.1ºC
1.535
3.5E-20mmHg at 25°C