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Monomethyl fumarate

Monomethyl fumarate structure

CAS No:
2756-87-8
Formula:
C5H6O4
Chemical Name:
Monomethyl fumarate
Synonyms:
2-Butenedioic acid (2E)-,1-methyl ester;Fumaric acid,monomethyl ester;Fumaric acid,methyl ester;2-Butenedioic acid (E)-,monomethyl ester;2-Butenedioic acid (2E)-,monomethyl ester;Monomethyl fumarate;Methyl hydrogen fumarate;(E)-4-Methoxy-4-oxobut-2-enoic acid;(E)-4-Methoxy-4-oxo-but-2-enoic acid
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

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Description

Off-White Solid

Monomethyl fumarate Basic Attributes

Molecular Weight：

130.1

Exact Mass：

130.10

EC Number：

220-412-6

HScode：

29171900

Characteristics

PSA：

63.6

XLogP3：

0.4

Density：

1.37 g/cm³ @ Temp: 20 °C

Melting Point：

143 °C

Boiling Point：

250°C at 760 mmHg

Flash Point：

108.9ºC

Refractive Index：

1.468

Vapor Pressure：

0.00706mmHg at 25°C

Safety Information

wgk germany：

hazard class code：

R41

safety instructions：

26-39

Marks：

Precautionary statement(s)：

P280, P305+P351+P338, P310

Hazard Statements：

H318

Monomethyl fumarate Use and Manufacturing

Fumaric Acid Monomethyl Ester is one of the most bioactive anti-psoriatic fumaric acid ester metabolite. Fumaric Acid Monomethyl Ester is potent nicotinic acid receptor agonist. Fumaric Acid Monomethy l Ester has also been shown to selectively stimulate of T helper 2 cytokine response.

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