4-amino-1-naphthol
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4-amino-1-naphthol
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CAS No:
2834-90-4
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Formula:
C10H9NO
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Chemical Name:
4-amino-1-naphthol
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Synonyms:
1-Amino-4-naphthol;4-amino-1-naphthol;4-Amino-1-naphthalenol;4-azanylnaphthalen-1-ol
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CAS No:
Safety Information
P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P330, P332+P313, P362, P403+P233, P405, P501
H302
|Danger|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P330, P332+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
4-amino-1-naphthol Use and Manufacturing
Using 1-naphthol as raw material, it is obtained by coupling and reduction. First, p-aminobenzenesulfonic acid is dissolved in sodium carbonate aqueous solution, cooled to below 15°C, and sodium nitrite is used in the presence of concentrated hydrochloric acid to prepare p-aminobenzenesulfonic acid diazonium salt. Then, the 1-naphthol sodium salt solution and the diazonium salt solution were coupled at 5-6°C. Then add sodium sulfonate and heat to 70°C for reduction, cool and filter, and wash the obtained crystal with 1% sodium sulfonate aqueous solution.
Used in organic synthesis.