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Pimethixene

Pimethixene structure

CAS No:
314-03-4
Formula:
C19H19NS
Chemical Name:
Pimethixene
Synonyms:
Piperidine,1-methyl-4-(9H-thioxanthen-9-ylidene)-;Piperidine,1-methyl-4-thioxanthen-9-ylidene-;1-Methyl-4-(9H-thioxanthen-9-ylidene)piperidine;BP 400;9-(N-Methyl-4′-piperidylene)thioxanthene;9-(N-Methyl-4′-piperidylidene)-thioxanthene;Pimethixene;Mepithiathene;9-(1-Methyl-4-piperidinylidene)thioxanthene;Calmixen;CGA 123427;BP 400S;Pimetixene;1-Methyl-4-thioxanthen-9-ylidenepiperidine;126464-53-7
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

Description

Pimethixene is an antihistamine and anticholinergic agent, that is often used to treat hyperactivity, anxiety, sleep disorders, and allergy.

1-methyl-4-(9-thioxanthenylidene)piperidine is a member of thioxanthenes.|Pimethixene is approved for use in Brazil and is marketed under the trade name Muricalm. It is an anticholinergic used in the treatment of bronchitis.

Pimethixene Basic Attributes

Molecular Weight：

293.428

Exact Mass：

293.43

EC Number：

236-141-1

UNII：

T46J20J26F

DSSTox ID：

DTXSID0048476

ATC Code：

R - Respiratory system

Characteristics

PSA：

28.5

XLogP3：

4.61660

Density：

1.192g/cm3

Melting Point：

120-122 °C @ Solvent: Hexane

Boiling Point：

439.7ºC at 760mmHg

Flash Point：

219.7ºC

Refractive Index：

1.661

Safety Information

Precautionary statement(s)：

P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, P501

Hazard Statements：

H302

GHS Classification：

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 39 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH Entry Terms：

1-methyl-4-thioxanthen-9-ylidenepiperidine

Computed Properties

Molecular Weight:293.4
XLogP3:3.9
Hydrogen Bond Acceptor Count:2
Exact Mass:293.12382078
Monoisotopic Mass:293.12382078
Topological Polar Surface Area:28.5
Heavy Atom Count:21
Complexity:382
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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pimethixene

CAS No.: 314-03-4

Grade: industrial Grade

Content: 98%

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