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Diazinon

Diazinon structure

Diazinon 

structure
  • CAS No:

    333-41-5

  • Formula:

    C12H21N2O3PS

  • Chemical Name:

    Diazinon

  • Synonyms:

    Phosphorothioic acid,O,O-diethyl O-[6-methyl-2-(1-methylethyl)-4-pyrimidinyl] ester;Phosphorothioic acid,O,O-diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl) ester;Phosphorothioic acid,O,O-diethyl 2-isopropyl-6-methyl-4-pyrimidinyl ester;G 301;ENT 19,507;G 24480;Diazinon;O,O-Diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl) phosphorothioate;Spectracide;Basudin;Sarolex;Basudin 10G;O,O-Diethyl O-(2-isopropyl-4-methyl-6-pyrimidyl) thionophosphate;ENT 19507;O,O-Diethyl O-(2-isopropyl-4-methyl-6-pyrimidinyl) phosphorothioate;Basudin 5G;Diazinon AG 500;O,O-Diethyl-O-(2-isopropyl-4-methyl-6-pyrimidyl) thiophosphate;Dimpylate;Garden Tox;Diethyl 2-isopropyl-4-methyl-6-pyrimidyl thionophosphate;Ciazinon;Dicid;Exodin;Flytrol;Dimpylat;Antigal;Dacutox;Dassitox;Galesan;Neocidol;Neocidol (oil);Oleodiazinon;Diethyl 2-isopropyl-4-methyl-6-pyrimidinyl phosphorothionate;Spectracide 25EC;Knox-out;Meodinon;Bassadinon;Disonex;Basudin S;Bazanon;Compass;Knox Out 2FM;Dizictol;Delzinon;Dazzel;Optimizer;Terminator;Diazinon 4E;Drawizon;Topclip 40;Dizinil;Compass (insecticide);Topclip Blue Shield;KFM Blowfly Dressing;Kleen-Dok;Topclip Blue;Cooper's Flystrike Powder;NSC 8938;Evict;Ortho Diazinon Ultra;Hi-Yield Imported Fire Ant Killer;Diazinon G;Basudin 600 EW;Dew 600EW;Nasr-Cidol;Akate Suro;27936-40-9;30583-38-1;65863-03-8

  • Categories:

    Agrochemicals  >  Insecticides

Description

Diazinon is an organophosphate insecticide widely used in agriculture to control a variety of pests. It acts by inhibiting the enzyme acetylcholinesterase, leading to the accumulation of acetylcholine in the nervous system of insects, ultimately resulting in their paralysis and death.

Diazinon Basic Attributes

304.35

304.35

206-373-8

2933599011

Characteristics

85.6

3.11

Liquid; light to dark brown. Sinks in water. Commercial solutions can contain ethanol/xylene/acetone with a flash point in the range 82-105° F.

1.116-1.118 g/cm3 @ Temp: 20 °C

<25 °C

83-84 °C @ Press: 2 x 10-3 Torr

104.4 °C

1.524

H2O: Slightly soluble . 0.004 g/100 mL

APPROX 4°C

Vapour pressure at 20°C: negligible

Oral-rat LD50: 66 mg/kg; Oral-Mouse LD50: 17 mg/kg

Decompose toxic phosphorus oxide, sulfur oxide, nitrogen oxide gas by heating

Faint ester-like odor

Safety Information

III

6.1(b)

UN 2783/2810

3

22-50/53-36-20/21/22-11-51/53

24/25-60-61-36-26-16-36/37

TF3325000

Xn;N,N,Xn,F

The warehouse is ventilated, low temperature and dry; stored and transported separately from food materials

SENSITIVE TO OXIDN ABOVE 100 DEG C; DEGRADATION ABOVE 120 DEG C

P201-P280-P301 + P312 + P330-P308 + P313

H302-H350-H410

Toxicity

most toxic

Diazinon Use and Manufacturing

Methods of Manufacturing

Methanol, hydrogen chloride and isobutyronitrile are reacted to form the corresponding imidate hydrochloride; treated with ammonia and converted into the corresponding amidine. Then, under basic conditions, amidine is condensed with ethyl acetoacetate to obtain pyrimidinol (4-hydroxy-2-isopropyl-6-methylpyrimidine). Pyrimidinol is heated to reflux in the presence of sodium carbonate in benzene or toluene, diethylthiophosphoryl chloride and copper nitrate are added, and condensation is obtained to obtain diazinon.

Uses

Diazinon is primarily used for controlling pests in crops such as fruits, vegetables, and ornamentals. It is also used in residential pest control, particularly for ants, cockroaches, and other household insects. However, due to environmental and health concerns, its usage has been restricted in many countries.

Computed Properties

Molecular Weight:304.35
XLogP3:3.8
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:304.10105071
Monoisotopic Mass:304.10105071
Topological Polar Surface Area:85.6
Heavy Atom Count:19
Complexity:307
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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