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11β-Hydroxyandrost-4-ene-3,17-dione

11β-Hydroxyandrost-4-ene-3,17-dione structure

CAS No:
382-44-5
Formula:
C19H26O3
Chemical Name:
11β-Hydroxyandrost-4-ene-3,17-dione
Synonyms:
Androst-4-ene-3,17-dione,11-hydroxy-,(11β)-;Androst-4-ene-3,17-dione,11β-hydroxy-;(11β)-11-Hydroxyandrost-4-ene-3,17-dione;Δ4-Androsten-11β-ol-3,17-dione;11β-Hydroxy-Δ4-androstene-3,17-dione;11β-Hydroxyandrost-4-ene-3,17-dione;4-Androstene-11β-ol-3,17-dione;4-Androsten-11β-ol-3,17-dione;Δ4-Androstene-11β-ol-3,17-dione;U 2826;11β-Hydroxy-4-androsten-3,17-dione;NSC 12167;NSC 17102

Description

11-Beta-hydroxyandrostenedione (4-Androsten-11β-ol-3,17-dione) is a steroid mainly found in the the adrenal origin (11β-hydroxylase is present in adrenal tissue, but absent in ovarian tissue). 11-Beta-hydroxyandrostenedione is a 11β-hydroxysteroid dehydrogenase (11βHSD) isozymes inhibitor. As 4-androstenedione increases, measuring plasma 11-Beta-hydroxyandrostenedione can distinguish the adrenal or ovarian origin of hyperandrogenism[1][2].

Solid

11beta-hydroxyandrost-4-ene-3,17-dione is an 11beta-hydroxy steroid, a 3-oxo steroid, a 17-oxo steroid and an androstanoid. It has a role as a human metabolite and a mouse metabolite.

11β-Hydroxyandrost-4-ene-3,17-dione Basic Attributes

Molecular Weight：

302.41

Exact Mass：

302.41

UNII：

41G81C896T

NSC Number：

17102|12167

DSSTox ID：

DTXSID8040931

Characteristics

PSA：

54.4

XLogP3：

1.27

Appearance：

Solid

Density：

1.2±0.1 g/cm3

Melting Point：

195.5-200.5 °C

Boiling Point：

475.3±45.0 °C at 760 mmHg

Flash Point：

255.4±25.2 °C

Refractive Index：

1.569

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

Drug Information

MeSH Entry Terms：

11 beta-hydroxyandrostenedione

11β-Hydroxyandrost-4-ene-3,17-dione Use and Manufacturing

Uses

4-Androsten-11β-ol-3,17-dione is a steroid hormone. An analog of Androstenedione (A637550).

Use Classification：

Lipids -> Sterol Lipids [ST] -> Steroids [ST02] -> C19 steroids (androgens) and derivatives [ST0202]

Computed Properties

Molecular Weight:302.4
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Exact Mass:302.18819469
Monoisotopic Mass:302.18819469
Topological Polar Surface Area:54.4
Heavy Atom Count:22
Complexity:577
Defined Atom Stereocenter Count:6
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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Guide of 11β-Hydroxyandrost-4-ene-3,17-dione

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties

11β-Hydroxyandrost-4-ene-3,17-dione

SDS

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