Metra
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Metra
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CAS No:
50-58-8
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Formula:
C12H17NO.C4H6O6
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Chemical Name:
Metra
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Synonyms:
Morpholine,3,4-dimethyl-2-phenyl-,(2S,3S)-,(2R,3R)-2,3-dihydroxybutanedioate (1:1);Morpholine,3,4-dimethyl-2-phenyl-,(2S-trans)-,[R-(R*,R*)]-2,3-dihydroxybutanedioate (1:1);Morpholine,3,4-dimethyl-2-phenyl-,(+)-,tartrate (1:1);Phendimetrazine tartrate;Phendimetrazine bitartrate;Plegine;Statobex;Metra;Prelu 2;2233-26-3;21102-82-9
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CAS No:
Description
Prelu-2 is a DEA Schedule III controlled substance. Substances in the DEA Schedule III have a potential for abuse less than substances in Schedules I or II and abuse may lead to moderate or low physical dependence or high psychological dependence.|Phendimetrazine Tartrate is a phenylalkylamine sympathomimetic amine with appetite depressant property. Phendimetrazine tartrate is a prodrug that is hydrolyzed to the active metabolite phenmetrazine, which competes with norepinephrine and dopamine for their presynaptic transporters, thereby blocks the reuptake of these monoamines at the neuronal junctions. As a result, this prolongs activities of dopamine and norepinephrine and leads to central nervous system (CNS) stimulation and metabolic effects, including appetite-suppression, decreased gastric acid secretion and increased blood pressure.
Metra Basic Attributes
491.44300
491.16400
200-051-0
6985IP0T80
1615
DTXSID70198165
C47667
2934999090
Safety Information
UN 2811 6.1 / PGIII
Missing Phrase - N15.00950417-P261-P305 + P351 + P338
H301-H315-H319-H332
|Danger|H301 (95.12%): Toxic if swallowed [Danger Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P310, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P405, and P501|Aggregated GHS information provided by 41 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Drug Information
A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here. (See all compounds classified as Central Nervous System Stimulants.)
Adipost
Phendimetrazine|Plegine, Prelu-2, Bontril, Melfiat, Statobex|1615|Schedule III - Substances in the DEA Schedule III have a potential for abuse less than substances in Schedules I or II and abuse may lead to moderate or low physical dependence or high psychological dependence.|No
Metra Use and Manufacturing
Appetite suppressant (systemic).
Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients
Computed Properties
Molecular Weight:341.36
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:341.14745207
Monoisotopic Mass:341.14745207
Topological Polar Surface Area:128
Heavy Atom Count:24
Complexity:311
Defined Atom Stereocenter Count:4
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes