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Thioglycolic acid

Thioglycolic acid structure

CAS No:
68-11-1
Formula:
C2H4O2S
Chemical Name:
Thioglycolic acid
Synonyms:
Acetic acid,2-mercapto-;Acetic acid,mercapto-;2-Mercaptoacetic acid;Glycolic acid,2-thio-;Thiovanic acid;2-Thioglycolic acid;Thioglycolic acid;α-Mercaptoacetic acid;Mercaptoacetic acid;2-Mercaptoethanoic acid;Sulfhydrylacetic acid;NSC 1894;TGA;2-Sulfanylacetic acid;7283-42-3;57755-20-1
Categories:
Cosmetic Ingredient > Antioxidant Ingredient

Description

Thioglycolic acid is a colorless liquid with a strong unpleasant odor like rotten eggs. Also known as mercaptoacetic acid, HSCH2COOH is a colorless liquid with a strong unpleasant odor. Used as a reagent for metals such as iron, molybdenum, silver, and tin,and in bacteriology.

Thioglycolic acid Basic Attributes

Molecular Weight：

92.11700

Exact Mass：

92.12

EC Number：

200-677-4

HScode：

2930909090

Characteristics

PSA：

76.10000

XLogP3：

0.00080

Appearance：

Thioglycolic acid appears as a colorless liquid with an unpleasant odor. Density 1.325 g / cm3. Used to make permanent wave solutions and depilatories. Corrosive to metals and tissue.

Density：

1.3253 g/cm³ @ Temp: 20 °C

Melting Point：

-16.5 °C

Boiling Point：

120 °C @ Press: 20 Torr

Flash Point：

126ºC

Refractive Index：

1.503-1.505

Water Solubility：

H2O: soluble

Storage Conditions：

2-8ºC

Vapor Pressure：

0.4 mm Hg ( 25 °C)

Vapor Density：

3.2 (vs air)

Toxicity：

LD50 orally in rats: 0.15 ml/kg (Deichmann, Mergard)

Flammability characteristics：

Class IIIB Combustible Liquid: Fl.P. at or above 200°F.

Explosive limit：

TLVWA 1 ppm (～3.8 mg/m3) (ACGIH).

Odor：

Strong, unpleasant odor

Safety Information

Packing level：

Hazard category：

Transport codes：

UN 1940/2436

wgk germany：

hazard class code：

R24/25; R26; R34

safety instructions：

S23-S25-S27-S28-S36/37-S45

RTECS Number：

AI5950000

Marks：

T+

Storage features：

Separated from strong oxidants, strong bases, food and feedstuffs and combustible substances. Keep in a well-ventilated room.

Stability/Shelf Life：

At room temperature, concentrations over approximately 70% in water tend to form 1-2% thioglycolides per month, which hydrolyze to the original free compound when made acid or alkaline. The 70% solution oxidizes in air, but is stable at room temperature when tightly closed. Thioglycolate salts may also lose purity on storage. The exclusion of air does not materially improve stability.

Precautionary statement(s)：

P280-P301 + P310 + P330-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338-P403 + P233

Hazard Statements：

H301 + H311 + H331-H314

Thioglycolic acid Use and Manufacturing

Thioglycolic acid (TGA) is the organic compound HSCH2CO2H. TGA is often called mercaptoacetic acid (MAA). It contains both a thiol (mercaptan) and carboxylic acid functional groups. It is a colorless liquid with a strongly unpleasant odor. TGA is miscible with polar organic solvents.

Computed Properties

Molecular Weight:92.12
XLogP3:0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:91.99320054
Monoisotopic Mass:91.99320054
Topological Polar Surface Area:38.3
Heavy Atom Count:5
Complexity:42.9
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Ethanol

Chloroacetic acid

Glycolic acid

Price Analysis

Make your Thioglycolic acid purchase based on the price and market insights! ECHEMI provides professional market insights with prices for you to make a better choice. Learn more on Thioglycolic acid prices .

Data: 2026-07-03
Price: 29000.00Yuan/ton
Change: 0

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