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Home > Encyclopedia > (-)-Ephedrine hydrochloride

(-)-Ephedrine hydrochloride

(-)-Ephedrine hydrochloride structure

(-)-Ephedrine hydrochloride 

structure
  • CAS No:

    50-98-6

  • Formula:

    C10H15NO.ClH

  • Chemical Name:

    (-)-Ephedrine hydrochloride

  • Synonyms:

    Benzenemethanol,α-[(1S)-1-(methylamino)ethyl]-,hydrochloride (1:1),(αR)-;Ephedrine,hydrochloride,(-)-;Benzenemethanol,α-[1-(methylamino)ethyl]-,hydrochloride,[R-(R*,S*)]-;Benzenemethanol,α-[(1S)-1-(methylamino)ethyl]-,hydrochloride,(αR)-;Ephedrine hydrochloride;l-Ephedrine hydrochloride;(-)-Ephedrine hydrochloride;l-α-[1-(Methylamino)ethyl]benzyl alcohol hydrochloride;Ephedrinium chloride;(1R,2S)-(-)-Ephedrine hydrochloride;L-erythro-Ephedrine hydrochloride;l-Ephedrine hydrochloride;Altusin;L-Ephedrine hydrochloride;(-)-Ephedrin hydrochloride;Ephedronguent;(1R,2S)-Ephedrine hydrochloride;CPDD 0047;Ephedral;Sanedrine;(1R,2S)-(-)-2-Ephedrinium hydrochloride;Enurace;877-36-1;7060-73-3;14992-57-5;15826-51-4

  • Categories:

    Active Pharmaceutical Ingredients  >  Respiratory Drugs

Description

colourless crystals or white crystalline powder


Ephedrine hydrochloride is an alkylbenzene.|A phenethylamine found in EPHEDRA SINICA. PSEUDOEPHEDRINE is an isomer. It is an alpha- and beta-adrenergic agonist that may also enhance release of norepinephrine. It has been used for asthma, heart failure, rhinitis, and urinary incontinence, and for its central nervous system stimulatory effects in the treatment of narcolepsy and depression. It has become less extensively used with the advent of more selective agonists.

(-)-Ephedrine hydrochloride Basic Attributes

201.69

201.092041

200-074-6

NLJ6390P1Z

DTXSID1045825

2939410010

Characteristics

32.26000

2.52080

218 °C

48.2 °F

2-8°C

-34 º (c=4, H2O)

Safety Information

NONH for all modes of transport

1

22-39/23/24/25-23/24/25-11

22-23-25-45-36/37-16-7

KB1750000

Xn,T,F

Stable, but light sensitive. Incompatible with strong oxidizing agents, strong acids, alkalies.

P301 + P312 + P330

H302

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P272, P273, P280, P301+P312, P302+P352, P321, P330, P333+P313, P363, and P501|Aggregated GHS information provided by 128 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|P264, P270, P301+P312, P330, and P501|Aggregated GHS information provided by 112 companies from 5 notifications to the ECHA C&L Inventory.

Drug Information

A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here. (See all compounds classified as Central Nervous System Stimulants.)|Drugs that act on adrenergic receptors or affect the life cycle of adrenergic transmitters. Included here are adrenergic agonists and antagonists and agents that affect the synthesis, storage, uptake, metabolism, or release of adrenergic transmitters. (See all compounds classified as Adrenergic Agents.)|Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. (See all compounds classified as Sympathomimetics.)|Drugs used to cause constriction of the blood vessels. (See all compounds classified as Vasoconstrictor Agents.)

Ephedrine

(-)-Ephedrine hydrochloride Use and Manufacturing

Uses

antidyskinetic

Benzenemethanol, .alpha.-[(1R)-1-(methylamino)ethyl]-, hydrochloride (1:1), (.alpha.S)-rel-: ACTIVE

Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients

Computed Properties

Molecular Weight:201.69
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:201.0920418
Monoisotopic Mass:201.0920418
Topological Polar Surface Area:32.3
Heavy Atom Count:13
Complexity:121
Defined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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