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Aminopentamide

Aminopentamide structure

CAS No:
60-46-8
Formula:
C19H24N2O
Chemical Name:
Aminopentamide
Synonyms:
Benzeneacetamide,α-[2-(dimethylamino)propyl]-α-phenyl-;Valeramide,4-(dimethylamino)-2,2-diphenyl-;α-[2-(Dimethylamino)propyl]-α-phenylbenzeneacetamide;Aminopentamide;Dimevamide;α,α-Diphenyl-γ-dimethylaminovaleramide;Valeramide-OM;Centrine;dl-Aminopentamide;BL 139;5985-87-5
Categories:
Active Pharmaceutical Ingredients > Digestive System Drugs

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Description

4-(dimethylamino)-2,2-diphenylpentanamide is a diarylmethane.

Aminopentamide Basic Attributes

Molecular Weight：

296.40666

Exact Mass：

296.41

EC Number：

200-479-8

UNII：

661TMO8UM4|HI3DVH9WMI

DSSTox ID：

DTXSID2057605

HScode：

2924299090

Characteristics

PSA：

46.33000

XLogP3：

3.49850

Density：

1.069±0.06 g/cm3 (20 ºC 760 Torr)

Melting Point：

137 °C

Boiling Point：

467.7ºC at 760 mmHg

Flash Point：

236.6ºC

Refractive Index：

1.564

Collision Cross Section：

169.6 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Drug Information

MeSH Entry Terms：

aminopentamide

Aminopentamide Use and Manufacturing

This product is a synthetic substitute for atropine. It has antispasmodic, reduces gastric acid secretion, and can relieve hyperactivity of the digestive tract. Its intensity of action is similar to that of atropine. It is used to treat duodenal ulcer, acute gastritis and pyloric spasm.

Computed Properties

Molecular Weight:296.4
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:296.188863393
Monoisotopic Mass:296.188863393
Topological Polar Surface Area:46.3
Heavy Atom Count:22
Complexity:336
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes