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6-CARBOXYFLUORESCEINDIACETATE

6-CARBOXYFLUORESCEINDIACETATE structure

6-CARBOXYFLUORESCEINDIACETATE 

structure
  • CAS No:

    3348-03-6

  • Formula:

    C25H16O9

  • Chemical Name:

    6-CARBOXYFLUORESCEINDIACETATE

  • Synonyms:

    6-CFDA;6-FAMDA;6-FAMDIACETATE;6-CARBOXYFLUORESCEINDIACETATE;6-CARBOXYFLUORESCEINEDIACETATE;6-CARBOXY-DI-O-ACETYLFLUORESCEIN;6-Carboxy-di-O-acetylfluorescein,6-CFDA;6-Carboxyfluoresceindiacetate,6-CFDA,6-Carboxy-di-O-acetylfluorescein;3',6'-diacetyloxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxylicacid;3',6'-diacetyloxy-1-oxo-spiro[2-benzofuran-3,9'-xanthene]-5-carboxylicacid

Description

6-CFDA is fluorescent polyanionic probe, and its derivatives such as 2′,7′-bis (2-carboxyethyl)-5(6)-carboxyfluorescein are used to measure changes in intracellular pH (pHi) and processes such as dendrimer aggregation and absorption.

6-CARBOXYFLUORESCEINDIACETATE Basic Attributes

460.389

460.079437

DTXSID80187121

2932999099

Characteristics

125.43000

2.45

1.6±0.1 g/cm3

152–153°C

701.6±60.0 °C at 760 mmHg

245.1±26.4 °C

1.702

2-8ºC

Safety Information

NONH for all modes of transport

3

Drug Information

6-carboxy-3',6'-diacetylfluorescein

6-CARBOXYFLUORESCEINDIACETATE Use and Manufacturing

6-CARBOXYFLUORESCEIN DIACETATE is used to differentiate viable cells from apoptotic cells. Live cells that are not apoptotic accumulate 6-carboxyfluorescein but do not accumulate annexin

Computed Properties

Molecular Weight:460.4
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:5
Exact Mass:460.07943208
Monoisotopic Mass:460.07943208
Topological Polar Surface Area:125
Heavy Atom Count:34
Complexity:828
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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