1-Bromo-2-naphthalenecarboxaldehyde
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1-Bromo-2-naphthalenecarboxaldehyde
structure -
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CAS No:
3378-82-3
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Formula:
C11H7BrO
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Chemical Name:
1-Bromo-2-naphthalenecarboxaldehyde
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Synonyms:
2-Naphthalenecarboxaldehyde,1-bromo-;2-Naphthaldehyde,1-bromo-;1-Bromo-2-naphthalenecarboxaldehyde;1-Bromo-2-naphthaldehyde;1-Bromonaphthalene-2-carbaldehyde
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CAS No:
1-Bromo-2-naphthalenecarboxaldehyde Basic Attributes
235.08
235.08
222-180-1
DTXSID60187442
2913000090
Safety Information
NONH for all modes of transport
3
36/37/38
S26-S37/39
Xi: Irritant;
P261-P305 + P351 + P338
H315-H319-H335
|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 40 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
1-Bromo-2-naphthalenecarboxaldehyde Use and Manufacturing
In a 2-L reactor, 4-methylmorpholine N-oxide (61.4 g, 524 mmol), a molecular sieve (200 g), and acetonitrile (1.2 L) were placed and stirred for 30 min at 0° C. under a nitrogen atmosphere. Intermediate 4-a (78 g, 262 mmol) was added, followed by stirring at room temperature for 6 hours. After completion of the reaction, the reaction mixture was filtered and washed with methylene chloride. The filtrate was concentrated and then isolated through column chromatography to afford Intermediate 4-b (45 g): yield 73percent
Computed Properties
Molecular Weight:235.08
XLogP3:3.3
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:233.96803
Monoisotopic Mass:233.96803
Topological Polar Surface Area:17.1
Heavy Atom Count:13
Complexity:193
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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1-Bromo-2-naphthalenecarboxaldehyde
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