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Embramine

Embramine structure

CAS No:
3565-72-8
Formula:
C18H22BrNO
Chemical Name:
Embramine
Synonyms:
Ethanamine,2-[1-(4-bromophenyl)-1-phenylethoxy]-N,N-dimethyl-;Ethylamine,2-[(p-bromo-α-methyl-α-phenylbenzyl)oxy]-N,N-dimethyl-;2-[1-(4-Bromophenyl)-1-phenylethoxy]-N,N-dimethylethanamine;2-[(p-Bromo-α-methyl-α-phenylbenzyl)oxy]-N,N-dimethyl ethylamine;1-(2-Dimethylaminoethoxy)-1-(p-bromophenyl)-1-phenylethane;Embramine;[2-[1-(4-Bromophenyl)-1-phenylethoxy]ethyl]dimethylamine
Categories:
Organic Chemistry > Amides

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Description

Embramine is a monoethanolamine used as an antihistamine and anticholinergic.

Embramine is a diarylmethane.

Embramine Basic Attributes

Molecular Weight：

348.27738

Exact Mass：

348.28

Characteristics

PSA：

12.5

XLogP3：

4.29080

Density：

1.234g/cm3

Boiling Point：

166 °C

Flash Point：

199.2ºC

Refractive Index：

1.561

Drug Information

MeSH：

Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood. (See all compounds classified as Histamine H1 Antagonists.)

MeSH Entry Terms：

bromadryl

Computed Properties

Molecular Weight:348.3
XLogP3:4.2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:347.08848
Monoisotopic Mass:347.08848
Topological Polar Surface Area:12.5
Heavy Atom Count:21
Complexity:296
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes