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Rubrofusarin

Rubrofusarin structure

CAS No:
3567-00-8
Formula:
C15H12O5
Chemical Name:
Rubrofusarin
Synonyms:
4H-Naphtho[2,3-b]pyran-4-one,5,6-dihydroxy-8-methoxy-2-methyl-;Rubrofusarin;5,6-Dihydroxy-8-methoxy-2-methyl-4H-naphtho[2,3-b]pyran-4-one;NSC 258316;1402-22-8
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

Description

ChEBI: A member of the class of benzochromenones that is benzo[g]chromen-4-one carrying two additional hydroxy substituents at positions 5 and 6 as well as methyl and methoxy substituents at positions 2 and 8 respectively. An orange polyketide pigmen that is a common intermediate in many different fungal biosynthetic pathways.

Rubrofusarin is a member of the class of benzochromenones that is benzo[g]chromen-4-one carrying two additional hydroxy substituents at positions 5 and 6 as well as methyl and methoxy substituents at positions 2 and 8 respectively. An orange polyketide pigment that is a common intermediate in many different fungal biosynthetic pathways. It has a role as a fungal metabolite, a biological pigment and an EC 1.14.18.1 (tyrosinase) inhibitor. It is a benzochromenone, a polyketide, an aromatic ether and a member of phenols. It is a conjugate acid of a rubrofusarin(1-).

Rubrofusarin Basic Attributes

Molecular Weight：

272.256

Exact Mass：

272.25

UNII：

533T23P5CF

NSC Number：

258316

DSSTox ID：

DTXSID90189171

Characteristics

PSA：

XLogP3：

Density：

1.432±0.06 g/cm3(Predicted)

Melting Point：

210-211 °C

Drug Information

MeSH Entry Terms：

5,6-dihydroxy-8-methoxy-2-methyl-4H-benzo(g)chromen-4-one

Computed Properties

Molecular Weight:272.25
XLogP3:3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:272.06847348
Monoisotopic Mass:272.06847348
Topological Polar Surface Area:76
Heavy Atom Count:20
Complexity:432
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes