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(+)-Isoalantolactone

(+)-Isoalantolactone structure

(+)-Isoalantolactone 

structure
  • CAS No:

    470-17-7

  • Formula:

    C15H20O2

  • Chemical Name:

    (+)-Isoalantolactone

  • Synonyms:

    Naphtho[2,3-b]furan-2(3H)-one,decahydro-8a-methyl-3,5-bis(methylene)-,(3aR,4aS,8aR,9aR)-;Eudesma-4(14),11(13)-dien-12-oic acid,8β-hydroxy-,γ-lactone;Isoalantolactone;Naphtho[2,3-b]furan-2(3H)-one,decahydro-8a-methyl-3,5-bis(methylene)-,[3aR-(3aα,4aα,8aβ,9aα)]-;(3aR,4aS,8aR,9aR)-Decahydro-8a-methyl-3,5-bis(methylene)naphtho[2,3-b]furan-2(3H)-one;(+)-Isoalantolactone;Isoallantolactone;Isohelenin;5αH-Eudesma-4(15),11(13)-dien-12,8β-olide;NSC 241036;26380-84-7

  • Categories:

    Biochemical Engineering  >  Chinese Herbs

Description

Isoalantolactone is an apoptosis inducer, which also acts as an alkylating agent.


Isoalantolactone is a sesquiterpene lactone of the eudesmanolide group. It has been isolated from Inula helenium. It has a role as an apoptosis inducer, an antifungal agent and a plant metabolite. It is a sesquiterpene lactone and a eudesmane sesquiterpenoid.

(+)-Isoalantolactone Basic Attributes

232.32

232.32

BYH07P620U

241036

29322090

Characteristics

26.3

3.4

1.1±0.1 g/cm3

157 °C (decomp)

364.9°C at 760 mmHg

152.7±25.3 °C

1.527

1.63E-05mmHg at 25°C

Safety Information

40

22-36

Xn

Drug Information

isoalantolactone

Computed Properties

Molecular Weight:232.32
XLogP3:3.4
Hydrogen Bond Acceptor Count:2
Exact Mass:232.146329876
Monoisotopic Mass:232.146329876
Topological Polar Surface Area:26.3
Heavy Atom Count:17
Complexity:409
Defined Atom Stereocenter Count:4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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