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Seneciphylline

Seneciphylline structure

CAS No:
480-81-9
Formula:
C18H23NO5
Chemical Name:
Seneciphylline
Synonyms:
[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione,3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-methyl-5-methylene-,(3Z,6R,14aR,14bR)-;Seneciphylline;Senecionan-11,16-dione,13,19-didehydro-12-hydroxy-;(3Z,6R,14aR,14bR)-3-Ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-methyl-5-methylene[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione;Jacodine;[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione,3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-methyl-5-methylene-,[6R-(3Z,6R*,14aR*,14bR*)]-;Seneciphyllin;Seneciophylline;α-Longilobine;NSC 30622
Categories:
Natural Products > Alkaloids

Description

Seneciphylline is a toxic pyrrolizidine alkaloid in Senecio plants[1]. Seneciphylline significantly increases the activities of epoxide hydrase and glutathione-S-transferase but causes reduction of cytochrome P-450 and related monooxygenase activities[2].

Seneciphylline Basic Attributes

Molecular Weight：

333.38

Exact Mass：

333.38

EC Number：

610-407-0

Characteristics

PSA：

76.1

XLogP3：

-1.88 @ 25 deg C

Appearance：

Seneciphylline is a white powder. (NTP, 1992)

Density：

1.3±0.1 g/cm3

Melting Point：

-218-217 °C

Boiling Point：

577.7±50.0 °C at 760 mmHg

Flash Point：

303.2±30.1 °C

Refractive Index：

1.581

Water Solubility：

In water, 1X10+6 mg/L @ 25 deg C /Estimated/

Storage Conditions：

-20°C

Vapor Pressure：

1.2X10-12 mm Hg @ 25 deg C /Estimated/

Specific rotation：

D -128° (chloroform)

Safety Information

Packing level：

III

Hazard category：

6.1(b)

Transport codes：

1544

wgk germany：

hazard class code：

23/24/25-25

safety instructions：

1-20-24/25-45

Marks：

Stability/Shelf Life：

Stable, but reacts with oxygen in the air. Incompatible with alkali, oxidizing agents. Store under inert gas.

Precautionary statement(s)：

Missing Phrase - N15.00950417

Hazard Statements：

H301

Recommended Suppliers of Seneciphylline

HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

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SENECIPHYLLINE

CAS No.: 480-81-9

Content: 99.00%

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Shaanxi Dideu Medichem Co. Ltd Contact Supplier

CN
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SENECIPHYLLIN

CAS No.: 480-81-9

Grade: Industrial Grade

Content: 99%

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Guide of Seneciphylline

Description
Basic Attributes
Characteristics
Safety Information
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