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(+)-SYLVATESMIN

(+)-SYLVATESMIN structure

(+)-SYLVATESMIN 

structure
  • CAS No:

    487-39-8

  • Formula:

    C21H24O6

  • Chemical Name:

    (+)-SYLVATESMIN

  • Synonyms:

    Phillygenin;Phillygenol;Forsythigenol;(+)-Phillygenin;Epipinoresinolmethylether;4-[(1S,3aR,4R,6aR)-4-(3,4-Dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenol;(1S,3aβ,6aβ)-1β-(3-Methoxy-4-hydroxyphenyl)-4α-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan;4-[[(1S)-4α-(3,4-Dimethoxyphenyl)-3aβ,4,6,6aβ-tetrahydro-1H,3H-furo[3,4-c]furan]-1β-yl]-2-methoxyphenol;(1S)-1β-(3-Methoxy-4-hydroxyphenyl)-4α-(3,4-dimethoxyphenyl)-3aβ,4,6,6aβ-tetrahydro-1H,3H-furo[3,4-c]furan;Phenol,4-

  • Categories:

    Biochemical Engineering  >  Chinese Herbs

Description

Phillygenin is an active ingredient from Forsythia with many medicinal properties, such as antioxidant, reducing blood lipid, inhibition of low density lipoprotein oxidation.In vitro : 1) Phillygenin shows a greater inhibition on mouse B16 melanoma cells potential than vincristine.2) phillygenin had notable scavenging activity against DPPH, ABTS radicals, as well as potent reducing power in FRAP assay.In vivo: The reference for rat is 5.6 mg/m l ( i.v).

(+)-SYLVATESMIN Basic Attributes

372.41166

372.157288

886IAL08GN

DTXSID80197588

Characteristics

66.4

2.6

1.2±0.1 g/cm3

133℃

534.9ºC at 760mmHg

277.3±30.1 °C

1.570

Drug Information

phillygenin

Computed Properties

Molecular Weight:372.4
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:372.15728848
Monoisotopic Mass:372.15728848
Topological Polar Surface Area:66.4
Heavy Atom Count:27
Complexity:487
Defined Atom Stereocenter Count:4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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