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Disodium p-nitrophenyl phosphate

Disodium p-nitrophenyl phosphate structure

Disodium p-nitrophenyl phosphate 

structure
  • CAS No:

    4264-83-9

  • Formula:

    C6H6NO6P.2Na

  • Chemical Name:

    Disodium p-nitrophenyl phosphate

  • Synonyms:

    Phosphoric acid,mono(4-nitrophenyl) ester,sodium salt (1:2);Phosphoric acid,mono(p-nitrophenyl) ester,disodium salt;Phosphoric acid,mono(4-nitrophenyl) ester,disodium salt;Phenol,p-nitro-,di-H phosphate,disodium salt;Phenol,p-nitro-,phosphate disodium salt;Disodium p-nitrophenyl phosphate;p-Nitrophenylphosphate sodium salt;p-Nitrophenyl phosphate disodium salt;Disodium 4-nitrophenyl phosphate;p-Nitrophenyl disodium phosphate;4-Nitrophenyl phosphate disodium salt;p-NPP disodium salt;Disodium mono(4-nitrophenyl) phosphate

  • Categories:

    Organic Chemistry  >  Amides

Description

PNPP is a non-proteinaceous chromogenic substrate for alkaline and acid phosphatases used in ELISA and conventional spectrophotometric assays.

Disodium p-nitrophenyl phosphate Basic Attributes

263.05

218.993271

5324661

224-246-5

DTXSID3063380

2919900090

Characteristics

118

white to pale yellow tablets

1.7±0.1 g/cm3

>300 °C(lit.)

457.8°C at 760 mmHg

230.7±29.3 °C

1.617

Miscible with water. Immiscible with ethanol and acetone.

2-8°C

Safety Information

1759

3

36/38-36/37/38-48/22-41-38-21/22

26-36-24/25-23-36/37/39

Xi,Xn

Stable, but may be light sensitive. Incompatible with strong acids, strong bases, strong oxidizing agents.

P260-P280-P305 + P351 + P338 + P310

H290-H315-H318-H373

|Danger|H290 (33.33%): May be corrosive to metals [Warning Corrosive to Metals]|P234, P260, P264, P270, P280, P301+P312, P302+P352, P305+P351+P338, P310, P314, P321, P330, P332+P313, P362, P390, P404, and P501|Aggregated GHS information provided by 5 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

4-aminophenylphosphate

Disodium p-nitrophenyl phosphate Use and Manufacturing

Uses

Determination of the chromogenic substrate of phosphatase; determination of the chromogenic substrate of acidic and alkaline phosphatases; the reaction can produce yellow end products, which can be read at a wavelength of 405 nm, and the reaction can be terminated by a 3 N NaOH solution.

Phosphoric acid, mono(4-nitrophenyl) ester, sodium salt (1:2): ACTIVE

Computed Properties

Molecular Weight:263.05
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:262.95716241
Monoisotopic Mass:262.95716241
Topological Polar Surface Area:118
Heavy Atom Count:16
Complexity:238
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes

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