N,N′-Dibutyl-1,6-hexanediamine

228.42

228.42

225-417-7

846A8RML53

2927|2735

DTXSID6038823

2921290000

24.1

4.10800

Hexamethylenediamine, n,n'-dibutyl- appears as a liquid. (EPA, 1998)

0.825 g/cm³ @ Temp: 25 °C

137-140 °C @ Press: 3-4 Torr

>110°C

n20/D 1.451(lit.)

No rapid reaction with air. No rapid reaction with water.

Amines, Phosphines, and Pyridines

N,N'-DIBUTYLHEXAMETHYLENEDIAMINE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

II

6.1

UN2927

36/37/38-34-26-14

26-36/37/39-45-23

MO1250000

T+

P260, P264, P271, P280, P284, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P320, P321, P363, P403+P233, P405, P501

H314

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

... May react violently with water.

(Non-Specific -- Alkylamine, n.o.s. (Corrosive)) Flammable or poisonous gases may accumulate in tanks or hopper cars. (EPA, 1998)

|Danger|H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]|P260, P264, P271, P280, P284, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P320, P321, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)

(Non-Specific -- Alkylamine, n.o.s. (Corrosive)) Do not touch spilled material; stop leak if you can do so without risk. Small spills: absorb with sand or other noncombustible absorbent material and place into containers for later disposal. Small dry spills: with clean shovel place material into clean, dry container and cover; move containers from spill area. Large spills: dike far ahead of spill for later disposal. Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. (EPA, 1998)

For emergency situations, wear a positive pressure, pressure-demand, full facepiece self-contained breathing apparatus (SCBA) or pressure- demand supplied air respirator with escape SCBA and a fully-encapsulating, chemical resistant suit. (EPA, 1998)

To fight small fires, use dry chemical, carbon dioxide, water spray, or foam. To fight large fires, use water spray, fog, or foam.

SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

A severe eye, skin, and mucous membrane irritant.

Releases of CERCLA hazardous substances are subject to the release reporting requirement of CERCLA section 103, codified at 40 CFR part 302, in addition to the requirements of 40 CFR part 355. N,N-Dibutyl-hexamethylenediamine is an extremely hazardous substance (EHS) subject to reporting requirements when stored in amounts in excess of its threshold planning quantity (TPQ) of 500 lbs.

LD50 Rat ihl 220 mg/cu m/4 hr

(Non-Specific -- Corrosive Alkali) Acute circulatory shock; burns in mouth, throat, and esophagus; suffocation due to glottal or laryngeal swelling; perforation and inflammation of the esophagus and the tracheobronchial tree; aspiration pneumonia. Delayed stricture (scar) formation causing problems with swallowing, and stomach filling and emptying; strong alkalis are markedly corrosive and penetrating to skin and mucous membranes. (EPA, 1998)

Warning: Hexamethylenediamine, N,N'-dibutyl- is corrosive.Caution is advised. Signs and Symptoms of Hexamethylenediamine, N,N'-Dibutyl- Exposure: Acute exposure to hexamethylenediamine, N,N'-dibutyl may result in irritation and burning of the skin, eyes, and mucous membranes. Light-headedness, drowsiness, slurred speech, pupillary dilation, increased salivation, dysphagia (difficulty swallowing), abdominal pain, and spontaneous vomiting may occur. Stridor (high-pitched, noisy respirations), dyspnea (shortness of breath), and pulmonary edema are also common. Apathy and mental confusion may develop, with progression to coma and death. Emergency Life-Support Procedures: Acute exposure to hexamethylenediamine, N,N'-dibutyl may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination. Inhalation Exposure: 1. Move victims to fresh air. Emergency personnel should avoid self-exposure to hexamethylenediamine, N,N'-dibutyl. 2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support. 3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures. 4. Transport to a health care facility. Dermal/Eye Exposure: 1. Remove victims from exposure. Emergency personnel should avoid self-exposure to hexamethylenediamine, N,N'-dibutyl. 2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support. 3. Remove and isolate contaminated clothing as soon as possible. 4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 30 minutes. 5. Wash exposed skin areas thoroughly with water. 6. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures. 7. Transport to a health care facility. Ingestion Exposure: 1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support. 2. DO NOT induce vomiting or attempt to neutralize! 3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures. 4. Activated charcoal may be administered if victims are conscious and alert. Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water. 5. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults, 250 mL (8 oz or 1 cup). Water or milk should be given only if victims are conscious and alert. 6. Transport to a health care facility. (EPA, 1998)

Human systemic effects by ingestion: acute circulatory shock; burns in the mouth, throat, and esophagus; suffocation due to glottal or laryngeal swelling; perforation and inflammation of the esophagus and the tracheobronchital tree; aspiration pneumonia. Scar formation can cause delayed problems with swallowing, and stomach filling and emptying. The immediate symptoms of ingestion are: visible burns in mouth, drooling, gagging, vomiting, chest and upper abdominal pain, difficulty in breathing, or apnea (respiratory arrest); collapse and cardiac arrest may occur.|Strong alkalies are markedly corrosive and penetrating to the skin and mucous membranes.

DBHMD

Petrochemical manufacturing|1,6-Hexanediamine, N1,N6-dibutyl-: ACTIVE