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NADPH

NADPH structure

CAS No:
53-57-6
Formula:
C21H30N7O17P3
Chemical Name:
NADPH
Synonyms:
Adenosine 5′-(trihydrogen diphosphate),2′-(dihydrogen phosphate),P′→5′-ester with 1,4-dihydro-1-β-D-ribofuranosyl-3-pyridinecarboxamide;Adenosine,2′-(dihydrogen phosphate) 5′-(trihydrogen pyrophosphate),5′→5′-ester with 1,4-dihydro-1-β-D-ribofuranosylnicotinamide;Dihydrocodehydrogenase II;NADPH;NADPH2;Reduced codehydrogenase II;Reduced nicotinamide adenine dinucleotide phosphate;Reduced triphosphopyridine nucleotide;Codehydrase II,reduced;Codehydrogenase II,reduced;Coenzyme II,reduced;Cozymase II,reduced;Nicotinamide-adenine dinucleotide phosphate,reduced;Triphosphopyridine nucleotide,reduced;TPNH;β-TPNH;β-NADPH;β-Nicotinamide-adenine-dinucleotide-phosphoric acid;51: PN: WO2004076659 FIGURE: 7 claimed sequence;3545-01-5;22046-90-8
Categories:
Biochemical Engineering > Enzymes and Coenzymes Drugs

Description

A coenzyme composed of ribosylnicotinamide 5′- phosphate coupled by pyrophosphate linkage to the 5′-phosphate adenosine 2′,5′-bisphosphate. The reduced from of NADP. It is an energy-storage form that can be transferred to the Calvin cycle where it participates in the production of carbohydrate.

Solid

NADPH is the reduced form of NADP+; used in anabolic reactions, such as lipid and nucleic acid synthesis, which require NADPH as a reducing agent. It has a role as a fundamental metabolite and a cofactor. It is a NAD(P)H and a NADP. It is a conjugate acid of a NADPH(4-).|Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)

NADPH Basic Attributes

Molecular Weight：

256.25514

Exact Mass：

745.42

EC Number：

200-177-6

UNII：

381Q4X082D

Characteristics

PSA：

394.57000

XLogP3：

-5.93

Appearance：

Solid

Density：

2.3±0.1 g/cm3

Boiling Point：

1175.1±75.0 °C at 760 mmHg

Flash Point：

664.5±37.1 °C

Refractive Index：

1.849

Collision Cross Section：

232.2 Å² [M]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|240.5 Å² [M+Na-H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|246.7 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|246.7 Å² [M-H]-

Drug Information

MeSH Entry Terms：

Coenzyme II

NADPH Use and Manufacturing

Uses

One of the biologically active forms of nicotinic acid. Differs from NAD by an additional phosphate group at the 2?position of the adenosine moiety. Serves as a coenzyme of hydrogenases and dehydrogenases. Present in living cells primarily in the r

Manufacturing Info：

Adenosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen phosphate), P'.fwdarw.5'-ester with 1,4-dihydro-1-.beta.-D-ribofuranosyl-3-pyridinecarboxamide: INACTIVE

Computed Properties

Molecular Weight:745.4
XLogP3:-6.8
Hydrogen Bond Donor Count:9
Hydrogen Bond Acceptor Count:22
Rotatable Bond Count:13
Exact Mass:745.09110351
Monoisotopic Mass:745.09110351
Topological Polar Surface Area:364
Heavy Atom Count:48
Complexity:1410
Defined Atom Stereocenter Count:8
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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Nadph 53-57-6

CAS No.: 53-57-6

Content: 95%

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Reduced coenzyme II NADPH; ent-NADPH; CAS 53-57-6

CAS No.: 53-57-6

Grade: Food Grade;Pharma Grade

Content: 99%

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Guide of NADPH

Description
Basic Attributes
Characteristics
Drug Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
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NADPH

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