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NADP

NADP structure

NADP 

structure
  • CAS No:

    53-59-8

  • Formula:

    C21H28N7O17P3

  • Chemical Name:

    NADP

  • Synonyms:

    Adenosine 5′-(trihydrogen diphosphate),2′-(dihydrogen phosphate),P′→5′-ester with 3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium,inner salt;Pyridinium,3-carbamoyl-1-β-D-ribofuranosyl-,hydroxide,5′→5′-ester with adenosine 2′-(dihydrogen phosphate) 5′-(trihydrogen pyrophosphate),inner salt;Adenosine 5′-(trihydrogen diphosphate),2′-(dihydrogen phosphate),P′→5′-ester with 3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium hydroxide,inner salt;Adenine-nicotinamide dinucleotide phosphate;Codehydrase II;Codehydrogenase II;Coenzyme II;NADP;NAD phosphate;Cozymase II;Nicotinamide-adenine dinucleotide phosphate;TPN;NADP+;β-NADP;β-TPN;Triphosphopyridine nucleotide;TPN (nucleotide);β-Nicotinamide adenine dinucleotide phosphate;52: PN: WO2004076659 FIGURE: 7 claimed sequence;Coenzyme 2;10213-33-9;25158-33-2;27678-67-7;162195-92-8

  • Categories:

    Biochemical Engineering  >  Enzymes and Coenzymes Drugs

Description

NADP is nicotinamide adenine dinucleotide phosphate, acting as a key cofactor for electron transfer in the metabolism of all organisms, being alternately oxidized (NADP+) and reduced (NADPH).


Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)

NADP Basic Attributes

743.41

743.075453

200-178-1

2924199090

Characteristics

368

H2O: 50 mg/mL, clear, slightly yellow

−20°C

Safety Information

3

36/37/38

26-36

UU3440000

Xi

Drug Information

Coenzyme II

NADP Use and Manufacturing

Methods of Manufacturing

Fresh sheep liver is prepared by grinding and filtering, extracting with hot water at 80°C, treating with trichloroacetic acid, neutralizing to pH 5-6 with alkali, washing by centrifugal precipitation, purifying the crude product and replacing it with cation exchange resin, eluting with shaving, and refining and drying.

Uses

Biochemical research.

Computed Properties

Molecular Weight:787.4
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:21
Rotatable Bond Count:12
Exact Mass:787.03934194
Monoisotopic Mass:787.03934194
Topological Polar Surface Area:373
Heavy Atom Count:50
Complexity:1280
Defined Atom Stereocenter Count:8
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes

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