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Pronethalol

Pronethalol structure

CAS No:
54-80-8
Formula:
C15H19NO
Chemical Name:
Pronethalol
Synonyms:
2-Naphthalenemethanol,α-[[(1-methylethyl)amino]methyl]-;2-Naphthalenemethanol,α-[(isopropylamino)methyl]-;α-[[(1-Methylethyl)amino]methyl]-2-naphthalenemethanol;Alderlin;Compound 38174;2-Isopropylamino-1-(naphth-2-yl)ethanol;Naphthylisoproterenol;NETH;Nethalide;Pronetalol;Pronethalol;Inetol;(±)-1-(2′-Naphthyl)-2-isopropylaminoethanol;dl-Pronethalol;(±)-Pronethalol;1-Naphthalen-2-yl-2-(propan-2-ylamino)ethanol;1-(Naphthalen-2-yl)-2-[(propan-2-yl)amino]ethan-1-ol;2238-85-9
Categories:
Organic Chemistry > Amides

Description

Pronethalol is a non-selective beta-adrenergic blocking agent, protect against and to reverse Digitalis-induced ventricular arrhythmias. Target: beta-adrenergic receptor

Pronethalol is a member of naphthalenes.

Pronethalol Basic Attributes

Molecular Weight：

229.323

Exact Mass：

229.32

DSSTox ID：

DTXSID8021193

HScode：

2922199090

Characteristics

PSA：

32.3

XLogP3：

3.26210

Density：

1.074g/cm3

Melting Point：

108 °C

Boiling Point：

322.4ºC at 760mmHg

Flash Point：

84.3ºC

Drug Information

MeSH Entry Terms：

naphthylisoproterenol

Pronethalol Use and Manufacturing

A non-selective beta blocker, not yet used in treatment due to carcinogenic properties. Pronetalol is a kind of beta adrenergic agonist, antiarrhythmic.

Computed Properties

Molecular Weight:229.32
XLogP3:3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:229.146664230
Monoisotopic Mass:229.146664230
Topological Polar Surface Area:32.3
Heavy Atom Count:17
Complexity:229
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes