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Tricin

Tricin structure

CAS No:
520-32-1
Formula:
C17H14O7
Chemical Name:
Tricin
Synonyms:
4H-1-Benzopyran-4-one,5,7-dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-;Flavone,4′,5,7-trihydroxy-3′,5′-dimethoxy-;Tricin;5,7-Dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-4H-1-benzopyran-4-one;4′,5,7-Trihydroxy-3′,5′-dimethoxyflavone;5,7,4′-Trihydroxy-3′,5′-dimethoxyflavone;NSC 294579;3′,5′-O-Dimethyltricetin
Categories:
Cosmetic Ingredient > Skin Protecting

Description

Tricin is a natural flavonoid present in large amounts in rice bran. Tricin can inhibit human cytomegalovirus (HCMV) replication by inhibiting CDK9. Tricin inhibits the proliferation and invasion of C6 glioma cells via the upregulation of focal-adhesion-finase (FAK)-targeting microRNA-7[1][2][3].

3',5'-di-O-methyltricetin is the 3',5'-di-O-methyl ether of tricetin. Known commonly as tricin, it is a constituent of rice bran and has been found to potently inhibit colon cancer cell growth. It has a role as an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor and a metabolite. It is a trihydroxyflavone, a dimethoxyflavone and a member of 3'-methoxyflavones. It derives from a tricetin. It is a conjugate acid of a 3',5'-di-O-methyltricetin(1-).

Tricin Basic Attributes

Molecular Weight：

330.29

Exact Mass：

330.29

UNII：

D51JZL38TQ

NSC Number：

294579

DSSTox ID：

DTXSID20199965

HScode：

2914509090

Characteristics

PSA：

105

XLogP3：

1.39

Density：

1.5±0.1 g/cm3

Melting Point：

288 °C

Boiling Point：

598.5±50.0 °C at 760 mmHg

Flash Point：

224.0±23.6 °C

Refractive Index：

1.671

Drug Information

MeSH Entry Terms：

5,7,4'-trihydroxy-3',5'-dimethoxy-flavone

Tricin Use and Manufacturing

Use Classification：

Polyketides [PK] -> Flavonoids [PK12] -> Flavones and Flavonols [PK1211]

Computed Properties

Molecular Weight:330.29
XLogP3:1.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:330.07395278
Monoisotopic Mass:330.07395278
Topological Polar Surface Area:105
Heavy Atom Count:24
Complexity:491
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of Tricin

HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

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Tricin

CAS No.: 520-32-1

Content: 99.00%

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Hangzhou Dawn Ray Pharmaceutical Co.,Ltd Contact Supplier

CN
5 YRS

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Tricin 10:1 Plant extract supplier made in china

CAS No.: 520-32-1

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Guide of Tricin

Description
Basic Attributes
Characteristics
Drug Information
Use and Manufacturing
Computed Properties
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