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Bilobetin

Bilobetin structure

Bilobetin 

structure
  • CAS No:

    521-32-4

  • Formula:

    C31H20O10

  • Chemical Name:

    Bilobetin

  • Synonyms:

    4H-1-Benzopyran-4-one,8-[5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-;3′′′,8-Biflavone,4′,5,5′′,7,7′′-pentahydroxy-4′′′-methoxy-;8-[5-(5,7-Dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one;Bilobetin;4′-Monomethylamentoflavone;4′-O-Methylamentoflavone

  • Categories:

    Biochemical Engineering  >  Chinese Herbs

Description

Bilobetin, an active component of Ginkgo biloba, can reduce blood lipids and improve the effects of insulin. Bilobetin ameliorated insulin resistance, increased the hepatic uptake and oxidation of lipids, reduced very-low-density lipoprotein triglyceride secretion and blood triglyceride levels, enhanced the expression and activity of enzymes involved in β-oxidation and attenuated the accumulation of triglycerides and their metabolites in tissues. Bilobetin also increased the phosphorylat


Solid

Bilobetin Basic Attributes

552.48

552.48

DTXSID70200095

Characteristics

163

4.20

Solid

1.6±0.1 g/cm3

225 °C

869.9±65.0 °C at 760 mmHg

291.9±27.8 °C

1.750

0.008998 mg/L @ 25 °C (est)

Drug Information

bilobetin

Computed Properties

Molecular Weight:552.5
XLogP3:5.4
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:4
Exact Mass:552.10564683
Monoisotopic Mass:552.10564683
Topological Polar Surface Area:163
Heavy Atom Count:41
Complexity:1060
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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