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Fraxin

Fraxin structure

Fraxin 

structure
  • CAS No:

    524-30-1

  • Formula:

    C16H18O10

  • Chemical Name:

    Fraxin

  • Synonyms:

    2H-1-Benzopyran-2-one,8-(β-D-glucopyranosyloxy)-7-hydroxy-6-methoxy-;Fraxin;8-(β-D-Glucopyranosyloxy)-7-hydroxy-6-methoxy-2H-1-benzopyran-2-one;Fraxetol 8-glucoside;Fraxetin 8-β-D-glucopyranoside;Fraxoside;7,8-Dihydroxy-6-methoxycoumarin 8-β-D-glucopyranoside;1328-88-7;4139-66-6;293738-09-7

  • Categories:

    Biochemical Engineering  >  Chinese Herbs

Description

Fraxin isolated from Acer tegmentosum, F. ornus or A. hippocastanum, is a glucoside of fraxetin and reported to exert potent anti-oxidative stress action[1], anti-inflammatory and antimetastatic properties. Fraxin shows its antioxidative effect through inhibition of cyclo AMP phosphodiesterase enzyme[2].


Fraxin is a beta-D-glucoside that is fraxetin attached to a beta-D-glucopyranosyl group at position 8 via a glycosidic linkage. It is a natural product isolated from the leaves of Fraxinus excelsior and exhibits potent hepatoprotective effects in vitro and in vivo. It has a role as a plant metabolite, an anti-inflammatory agent and a hepatoprotective agent. It is a beta-D-glucoside, a hydroxycoumarin and an aromatic ether. It derives from a fraxetin.

Fraxin Basic Attributes

370.31

370.31

208-355-5

V7M270Y072

DTXSID30200410

Characteristics

155

-0.6

Yellow powder

1.6±0.1 g/cm3

200 °C

722.2°C at 760 mmHg

267.1±26.4 °C

1.664

2-8°C

Safety Information

NONH for all modes of transport

3

DJ3091000

Drug Information

7,8-Dihydroxy-6-methoxycoumarin-8-beta-D-glucoside

Computed Properties

Molecular Weight:370.31
XLogP3:-0.6
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:4
Exact Mass:370.08999677
Monoisotopic Mass:370.08999677
Topological Polar Surface Area:155
Heavy Atom Count:26
Complexity:539
Defined Atom Stereocenter Count:5
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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