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Piperoxan

Piperoxan structure

Piperoxan 

structure
  • CAS No:

    59-39-2

  • Formula:

    C14H19NO2

  • Chemical Name:

    Piperoxan

  • Synonyms:

    Piperidine,1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]-;Piperidine,1-(1,4-benzodioxan-2-ylmethyl)-;Piperoxan;1,4-Benzodioxin,piperidine deriv.;1-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]piperidine;Fourneau 933;Benodaine;Piperoxane;F 933;933F;(RS)-Piperoxane;(±)-Piperoxane;165963-28-0

Description

A benzodioxane alpha-adrenergic blocking agent with considerable stimulatory action. It has been used to diagnose PHEOCHROMOCYTOMA and as an antihypertensive agent.

Piperoxan Basic Attributes

233.311

233.31

DTXSID1046269

Characteristics

21.7

2.25020

1.113

193 °C

118ºC

1.546

LD50 intraperitoneal in mouse: 175mg/kg

Drug Information

Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. (See all compounds classified as Antihypertensive Agents.)|Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma. (See all compounds classified as Adrenergic alpha-Antagonists.)

Benodain

Computed Properties

Molecular Weight:233.31
XLogP3:2.6
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:233.141578849
Monoisotopic Mass:233.141578849
Topological Polar Surface Area:21.7
Heavy Atom Count:17
Complexity:240
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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