Allylisopropylacetylurea
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Allylisopropylacetylurea
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CAS No:
528-92-7
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Formula:
C9H16N2O2
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Chemical Name:
Allylisopropylacetylurea
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Synonyms:
4-Pentenamide,N-(aminocarbonyl)-2-(1-methylethyl)-;Urea,(2-isopropyl-4-pentenoyl)-;N-(Aminocarbonyl)-2-(1-methylethyl)-4-pentenamide;Allylisopropylacetylcarbamide;Allylisopropylacetylurea;Apronal;(2-Isopropyl-4-pentenoyl)urea;Sedormid;Apronalide;2-Allyl-2-isopropylacetylurea;Isodormid;Alipronal;[2-(Propan-2-yl)pent-4-enoyl]urea
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CAS No:
Description
Apronal (Allylisopropylacetylurea, Apronalide) is a hypnotic and sedative drug that has been withdrawn in several countries due to side effects.
Apronal is a N-acylurea.|Apronalide is approved in Japan. Apronalide has been withdrawn from the market in many other countries due to patient development of thrombocytopenic purpura.
Allylisopropylacetylurea Use and Manufacturing
Allylisopropylacetylurea is used in a novel approach to cytochrome P-450 induction, through barbiturate-like activity.
Computed Properties
Molecular Weight:184.24
XLogP3:1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:184.121177757
Monoisotopic Mass:184.121177757
Topological Polar Surface Area:72.2
Heavy Atom Count:13
Complexity:212
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
