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Coixol

Coixol structure

Coixol 

structure
  • CAS No:

    532-91-2

  • Formula:

    C8H7NO3

  • Chemical Name:

    Coixol

  • Synonyms:

    2(3H)-Benzoxazolone,6-methoxy-;2-Benzoxazolinone,6-methoxy-;6-Methoxy-2(3H)-benzoxazolone;Coixol;6-Methoxy-2-benzoxazolinone;6-Methoxybenzoxazolinone;MBOA;6-MBOA;6-Methoxy-3H-benzoxazol-2-one;6-Methoxybenzoxazolin-2(3H)-one;6-Methoxybenzo[d]oxazol-2(3H)-one;13895-18-6;83144-55-2

  • Categories:

    Natural Products  >  Alkaloids

Description

Coixol is a natural product extracted from Coix Lachryma-Jobi var. ma-yuen.IC50 value:Target:In vitro: Confluent NCI-H292 cells were pretreated with oleic acid, linoleic acid, glyceryl trilinoleate, beta-stigmasterol or coixol for 30 min and then stimulated with PMA (phorbol 12-myristate 13-acetate), EGF (epidermal growth factor) or TNF-α (tumor necrosis factor-α) for 24 h. Coixol inhibited the expression of MUC5AC mucin gene and production of MUC5AC mucin protein, induced by EGF or TNF-


Solid


Coixol is a benzoxazole.

Coixol Basic Attributes

165.15

165.15

141041

DTXSID30201260

2934999090

Characteristics

47.6

1.07

light tan

1.3±0.1 g/cm3

151.5-152.5 °C

292.97°C (rough estimate)

1.563

2-8°C

Safety Information

3

22-24/25

DM5275200

Drug Information

6-MBOA

Computed Properties

Molecular Weight:165.15
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:165.042593085
Monoisotopic Mass:165.042593085
Topological Polar Surface Area:47.6
Heavy Atom Count:12
Complexity:195
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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