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Chlophedianol hydrochloride

pharmaceutical raw materials
Chlophedianol hydrochloride structure

Chlophedianol hydrochloride 

structure
  • CAS No:

    511-13-7

  • Formula:

    C17H20ClNO.ClH

  • Chemical Name:

    Chlophedianol hydrochloride

  • Synonyms:

    Benzenemethanol,2-chloro-α-[2-(dimethylamino)ethyl]-α-phenyl-,hydrochloride (1:1);Benzhydrol,2-chloro-α-[2-(dimethylamino)ethyl]-,hydrochloride;Benzenemethanol,2-chloro-α-[2-(dimethylamino)ethyl]-α-phenyl-,hydrochloride;SL 501;Chlophedianol hydrochloride;2-Chloro-α-[2-(dimethylamino)ethyl]benzhydrol hydrochloride;1-o-Chlorophenyl-1-phenyl-3-dimethylamino-1-propanol hydrochloride;α-(2-Dimethylaminoethyl)-o-chlorobenzhydrol hydrochloride;ULO;SK 74;Clofedanol hydrochloride;Detigon;Ulone;Refugal;Pectolitan;Coldrin;1-(2-Chlorophenyl)-3-(dimethylamino)-1-phenylpropan-1-ol hydrochloride

  • Categories:

    Active Pharmaceutical Ingredients  >  Respiratory Drugs

Description

Chlophedianol hydrochloride is a diarylmethane.

Chlophedianol hydrochloride Basic Attributes

326.26

325.100006

208-124-9

Characteristics

23.47000

4.32960

190-191 °C

429.8ºC at 760mmHg

213.7ºC

LD50 orally in rats: 350 mg/kg; s.c. in mice: 95 mg/kg (Lorenz)

Safety Information

III

6.1(b)

3249

25

36/37/39-45

DC7600000

T

P264, P270, P273, P301+P312, P330, P391, P501

H302

Drug Information

2-chloro-alpha-(2-dimethylaminoethyl)benzhydrol

Chlophedianol hydrochloride Use and Manufacturing

Uses

A centrally-acting cough suppressant. It has local anesthetic and antihistamine properties, and may have anticholinergic effects at high doses.

Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients

Computed Properties

Molecular Weight:326.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:325.1000197
Monoisotopic Mass:325.1000197
Topological Polar Surface Area:23.5
Heavy Atom Count:21
Complexity:291
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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