Taurodeoxycholic acid
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Taurodeoxycholic acid
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CAS No:
516-50-7
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Formula:
C26H45NO6S
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Chemical Name:
Taurodeoxycholic acid
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Synonyms:
Ethanesulfonic acid,2-[[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]amino]-;Taurodeoxycholic acid;Taurine,N-(3α,12α-dihydroxy-5β-cholan-24-oyl)-;Cholane,ethanesulfonic acid deriv.;2-[[(3α,5β,12α)-3,12-Dihydroxy-24-oxocholan-24-yl]amino]ethanesulfonic acid;Deoxycholyltaurine;Taurodesoxycholic acid;Deoxytaurocholic acid;Tudcabil;3α,12α-Dihydroxy-5β-cholanic acid-24-taurine;TDCA;125757-77-9;882214-17-7
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CAS No:
Description
ChEBI: A bile acid taurine conjugate of deoxycholic acid.
A bile salt formed in the liver by conjugation of deoxycholate with taurine, usually as the sodium salt. It is used as a cholagogue and choleretic, also industrially as a fat emulsifier.
Drug Information
Purifying or cleansing agents, usually salts of long-chain aliphatic bases or acids, that exert cleansing (oil-dissolving) and antimicrobial effects through a surface action that depends on possessing both hydrophilic and hydrophobic properties. (See all compounds classified as Detergents.)|Gastrointestinal agents that stimulate the flow of bile into the duodenum (cholagogues) or stimulate the production of bile by the liver (choleretic). (See all compounds classified as Cholagogues and Choleretics.)
Acid, Taurodeoxycholic
Taurodeoxycholic acid Use and Manufacturing
Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling.
Computed Properties
Molecular Weight:499.7
XLogP3:3.6
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:499.29675933
Monoisotopic Mass:499.29675933
Topological Polar Surface Area:132
Heavy Atom Count:34
Complexity:858
Defined Atom Stereocenter Count:9
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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