(+)-Conessine
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(+)-Conessine
structure -
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CAS No:
546-06-5
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Formula:
C24H40N2
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Chemical Name:
(+)-Conessine
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Synonyms:
Con-5-enin-3-amine,N,N-dimethyl-,(3β)-;Conessine;Con-5-enine,3β-(dimethylamino)-;Conkurchine,N,18-dihydrotrimethyl-;1H-Naphth[2′,1′:4,5]indeno[1,7a-c]pyrrole,con-5-enin-3-amine deriv.;(3β)-N,N-Dimethylcon-5-enin-3-amine;Neriine;Roquessine;Wrightine;Conessin;N′,18-Dihydro-N,N,N′-trimethylconkurchine;(+)-Conessine;NSC 119994
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CAS No:
Description
ChEBI: A steroid alkaloid that is con-5-enine substituted by a N,N-dimethylamino group at position 3. It has been isolated from the plant species of the family Apocynaceae.
Conessine is a steroid alkaloid that is con-5-enine substituted by a N,N-dimethylamino group at position 3. It has been isolated from the plant species of the family Apocynaceae. It has a role as an antibacterial agent, an antimalarial, a H3-receptor antagonist and a plant metabolite. It is a steroid alkaloid and a tertiary amino compound. It derives from a conanine.
Characteristics
6.5
5.71
white to tan
1.1±0.1 g/cm3
125.5 °C
450.4±45.0 °C at 760 mmHg
199.6±16.5 °C
1.564
ethanol: ≥2mg/mL
Store at RT
D20 +25.3° (c = 0.7 in abs alc)
195.4 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Safety Information
NONH for all modes of transport
3
36/37/38
26
GK7621000
Xi
P261-P305 + P351 + P338
H315-H319-H335
|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Computed Properties
Molecular Weight:356.6
XLogP3:4.9
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:356.319149284
Monoisotopic Mass:356.319149284
Topological Polar Surface Area:6.5
Heavy Atom Count:26
Complexity:609
Defined Atom Stereocenter Count:8
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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