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MONOMYRISTIN

MONOMYRISTIN structure

CAS No:
589-68-4
Formula:
C17H34O4
Chemical Name:
MONOMYRISTIN
Synonyms:
Tetradecanoic acid, 2,3-dihydroxypropyl ester;Myristic acid 2,3-dihydroxypropyl ester;(+)-L-Glycerol 1-myristate;(+)-Myristic acid (S)-2,3-dihydroxypropyl ester;1-O-Myristoyl-L-glycerol;1-Monotetradecanoyl-rac-glycerol, rac-1-Myristoylglycerol, DL-α-Myristin, Monomyristin;1-MYRISTOYL-RAC-GLYCEROL;1-MONOMYRISTIN
Categories:
Cosmetic Ingredient > Emulsifying Agent

Description

1-Monomyristin, extracted from Serenoa repens, inhibits the hydrolysis of 2-oleoylglycerol (IC50=32 μM) and fatty acid amide hydrolase (FAAH) activity (IC50=18 μM). 1-Monomyristin shows antibacterial activity against Staphylococcus aureus and Aggregatibacter actinomycetemcomitans and also antifungal activity against Candida albicans[1][2][3].

1-monomyristoylglycerol is a 1-monoglyceride with tetradecanoyl (myristoyl) as the acyl group. It has a role as a Caenorhabditis elegans metabolite. It is a 1-monoglyceride and a tetradecanoate ester.

It is soluble in organic solvents such as methanol, ethanol, and DMSO, and is derived from nutmeg.

ChEBI: A rac-1-monoacylglycerol that is composed of equal amounts of 1-myristoyl-sn-glycerol and 3-myristoyl-sn-glycerol.

MONOMYRISTIN Basic Attributes

Molecular Weight：

302.45

Exact Mass：

302.45

BRN：

1727502

EC Number：

248-329-0

NSC Number：

404225

DSSTox ID：

DTXSID3042005|DTXSID0042454

Color/Form：

White to Almost white

HScode：

2915.90.5050

Characteristics

PSA：

66.76000

XLogP3：

5.10

Density：

0.9748 (rough estimate)

Melting Point：

68-70 °C

Boiling Point：

363.47°C (rough estimate)

Flash Point：

141.3±16.7 °C

Refractive Index：

1.4230 (estimate)

Storage Conditions：

-20ºC

PKA：

13.16±0.20(Predicted)

Collision Cross Section：

183.5 Å² [M+Na]+

Critical Temperature & Pressure：

Sealed in dry,2-8°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

safety instructions：

22-24/25

Drug Information

MeSH Entry Terms：

1-monomyristin

MONOMYRISTIN Use and Manufacturing

Uses

α-Monomyristin, is used for the preparation of nonionic surfactant micelles. It is also a 1-monoglyceride of myristic acid, has antibacterial activity against several Gram-positive bacterial strains.

Manufacturing Info：

Tetradecanoic acid, monoester with 1,2,3-propanetriol: ACTIVE

Use Classification：

Cosmetics -> Emollient; Emulsifying

Computed Properties

Molecular Weight:302.4
XLogP3:5.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:16
Exact Mass:302.24570956
Monoisotopic Mass:302.24570956
Topological Polar Surface Area:66.8
Heavy Atom Count:21
Complexity:231
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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rac-Glycerol 1-myristate

CAS No.: 589-68-4

Content: 99.00%

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