2-Chloro-1-propene

76.52

76.52

1361376

209-187-5

50TXN55E4A

2456

DTXSID4040262

COLORLESS GAS OR LIQUID

0

2.00

2-chloropropene appears as a clear colorless volatile liquid. Less dense than water and insoluble in water. Vapors heavier than air.

0.9017 g/cm³ @ Temp: 20 °C

-137.4 °C

22.6 °C @ Press: 760 Torr

-20°C

1.398

INSOL IN WATER; SOL IN ETHER, ACETONE, BENZENE, CHLOROFORM

2-8°C

819 mm Hg at 25 deg C /from experimentally-derived coefficients/

2.63 (AIR= 1)

Inhalation-Mouse LC50: 267 g/m3

Flammable; the products of thermal decomposition or combustion contain poisonous phosgene and hydrogen chloride gas

Highly flammable. Insoluble in water.

Halogenated Organic Compounds

Highly Flammable

Halogenated aliphatic compounds, such as 2-CHLOROPROPENE, are moderately or very reactive. Halogenated organics generally become less reactive as more of their hydrogen atoms are replaced with halogen atoms. Low molecular weight haloalkanes are highly flammable and can react with some metals to form dangerous products. Low molecular weight haloalkenes are highly flammable, peroxidizable and may polymerize violently. They may react violently with aluminum. Materials in this group are incompatible with strong oxidizing and reducing agents. Also, they are incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.

LOWER 4.5% BY VOL; UPPER 16% BY VOL

I

3

UN 2456 3/PG 1

3

12-36/37

16-26-36

UC7200000

F+,Xi

Treasury is ventilated, low temperature and dry; stored and transported separately from oxidants and acids

Heated. Open flames can explode; mix with air to form explosive mixture

P210-P261-P305 + P351 + P338

H224-H319-H335

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Excerpt from ERG Guide 130P [Flammable Liquids (Water-Immiscible / Noxious)]: HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water. (ERG, 2016)|Flammable - 4th degree, Reactive - 1st degree

|Danger|H224 (100%): Extremely flammable liquid and vapor [Danger Flammable liquids]|P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P280, P301+P312, P302+P352, P303+P361+P353, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P370+P378, P403+P233, P403+P235, P405, and P501|Aggregated GHS information provided by 102 companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Excerpt from ERG Guide 130P [Flammable Liquids (Water-Immiscible / Noxious)]: As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions. LARGE SPILL: Consider initial downwind evacuation for at least 300 meters (1000 feet). FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)

Excerpt from ERG Guide 130P [Flammable Liquids (Water-Immiscible / Noxious)]: ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). All equipment used when handling the product must be grounded. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. A vapor-suppressing foam may be used to reduce vapors. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. Use clean, non-sparking tools to collect absorbed material. LARGE SPILL: Dike far ahead of liquid spill for later disposal. Water spray may reduce vapor, but may not prevent ignition in closed spaces. (ERG, 2016)

Excerpt from ERG Guide 130P [Flammable Liquids (Water-Immiscible / Noxious)]: Wear positive pressure self-contained breathing apparatus (SCBA). Structural firefighters' protective clothing will only provide limited protection. (ERG, 2016)|Personnel protection: ... Wear appropriate chemical protective gloves, boots and goggles. ... Wear positive pressure self-contained breathing apparatus when fighting fires involving this material.

FLAMMABLE, DANGEROUS FIRE RISK

If material on fire or involved in fire: Do not extinguish fire unless flow can be stopped or safely confined. Use water in flooding quantities as fog. Solid streams of water may spread fire. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use foam, dry chemical, or carbon dioxide.

If material not on fire and not involved in fire: Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Attempt to stop leak if without undue personnel hazard. Use water spray to knock-down vapors.|Personnel protection: Avoid breathing vapors. Keep upwind. ... Do not handle broken packages unless wearing appropriate personal protective equipment. Wash away any material which may have contacted the body with copious amounts of water or soap and water.

/GUIDE 130P: FLAMMABLE LIQUIDS (Non-Polar/Water-Immiscible/Noxious)/ Fire or Explosion: HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.|/GUIDE 130P: FLAMMABLE LIQUIDS (Non-Polar/Water-Immiscible/Noxious)/ Health: May cause toxic effects if inhaled or absorbed through skin. Inhalation or contact with material may irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.|/GUIDE 130P: FLAMMABLE LIQUIDS (Non-Polar/Water-Immiscible/Noxious)/ Public Safety: CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number listed on the inside back cover. As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate closed spaces before entering.|/GUIDE 130P: FLAMMABLE LIQUIDS (Non-Polar/Water-Immiscible/Noxious)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Structural firefighters' protective clothing will only provide limited protection.|For more DOT Emergency Guidelines (Complete) data for 2-CHLORO-1-PROPENE (8 total), please visit the HSDB record page.

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./|The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.|The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

| 2 - Materials that, under emergency conditions, can cause temporary incapacitation or residual injury.| 4 - Materials that rapidly or completely vaporize at atmospheric pressure and normal ambient temperature or that are readily dispersed in air and burn readily.| 0 - Materials that in themselves are normally stable, even under fire conditions.

moderately toxic

2-Chloro-1-propene's production and use as a chemical intermediate in organic synthesis and in the formulation of comonomers(1) may result in its release to the environment through various waste streams(SRC). 2-Chloro-1-propene may also be released to the environment in waste streams(SRC) during the production of allyl chloride(2,3).

TERRESTRIAL FATE: Based on a recommended classification scheme(1), an estimated Koc value of 35(SRC), determined from a structure estimation method(2), indicates that 2-chloro-1-propene will have very high mobility in soil(SRC). Volatilization of 2-chloro-1-propene should be important from moist soil surfaces(SRC) given an estimated Henry's Law constant of 7.0X10-2 atm-cu m/mole(SRC), using a fragment constant estimation method(3). Volatilization from dry soil surfaces(SRC) is expected based on a vapor pressure of 819 mm Hg(SRC), determined from experimentally-derived coefficients(4). Based on limited data, this compound is expected to be resistant to both anaerobic and aerobic biodegradation(SRC). In anaerobic and aerobic closed bottle tests, using a mixture of 12 chlorinated aliphatic compounds and a methanotroph-conditioned culture inoculum, 10% and 20% removal of 2-chloro-1-propene (initially present at 84 ug (anaerobic) and 30 ug (aerobic)), respectively, was reported after 60 days incubation(5).|AQUATIC FATE: Based on a recommended classification scheme(1), an estimated Koc value of 35(SRC), determined from a structure estimation method(2), indicates that 2-chloro-1-propene should not adsorb to suspended solids and sediment in water(SRC). 2-Chloro-1-propene is expected to volatilize from water surfaces(1,SRC) based on an estimated Henry's Law constant of 7.0X10-2 atm-cu m/mole(SRC), developed using a fragment constant estimation method(3). Estimated volatilization half-lives for a model river and model lake are 3 hours and 3 days, respectively(1,SRC). Measured half-lives for 2-chloro-1-propene in dilute (1 ppm, average solution depth of 6.5 cm) aqueous solution ranged from 29.7 to 35.8 minutes(4). According to a classification scheme(5), an estimated BCF value of 20(1,SRC), from a measured log Kow(6), suggests that bioconcentration in aquatic organisms is low(SRC). Based on limited data, this compound is expected to be resistant to both anaerobic and aerobic biodegradation(SRC). In anaerobic and aerobic closed bottle tests, using a mixture of 12 chlorinated aliphatic compounds and a methanotroph-conditioned culture inoculum, 10% and 20% removal of 2-chloro-1-propene (initially present at 84 ug (anaerobic) and 30 ug (aerobic)), respectively, was reported after 60 days incubation(7).|ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), 2-chloro-1-propene, which has a vapor pressure of 819 mm Hg at 25 °C(SRC), from experimentally-derived coefficients(2), will exist solely as a vapor in the ambient atmosphere. Vapor-phase 2-chloro-1-propene is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be about 1-2 days(3,SRC).

The rate constant for the vapor-phase reaction of 2-chloro-1-propene with photochemically-produced hydroxyl radicals has been estimated as 1.1X10-12 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1,SRC). This corresponds to an atmospheric half-life of about 1-2 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1,SRC).

An estimated BCF value of 20 was calculated for 2-chloro-1-propene(SRC), using a measured log Kow of 2.0(1) and a recommended regression-derived equation(2). According to a classification scheme(3), this BCF value suggests that bioconcentration in aquatic organisms is low(SRC).

Using a structure estimation method based on molecular connectivity indices(1), the Koc for 2-chloro-1-propene can be estimated to be about 35(SRC). According to a recommended classification scheme(2), this estimated Koc value suggests that 2-chloro-1-propene has very high mobility in soil(SRC).

Measured half-lives for 2-chloro-1-propene in dilute (1 ppm, average solution depth of 6.5 cm) aqueous solution ranged from 29.7 to 35.8 minutes(1). The time required for 50 and 90% evaporation of 2-chloro-1-propene from a dilute aqueous solution was 29 and 110 minutes, respectively(2). The Henry's Law constant for 2-chloro-1-propene is estimated as 7.0X10-2 atm-cu m/mole(SRC) using a fragment constant estimation method(3). This value indicates that 2-chloro-1-propene will volatilize rapidly from water surfaces(4,SRC). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec) is estimated as approximately 3 hours(4,SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec) is estimated as approximately 3 days(4,SRC). 2-Chloro-1-propene's values for vapor pressure, 819 mm Hg at 25 °C(SRC), from experimentally-derived coefficients(5), and Henry's Law constant(3,SRC) indicate that volatilization from dry and moist soil surfaces should occur(SRC).

The general population may be exposed to 2-chloro-1-propene via inhalation of ambient air and dermal contact with vapors and products containing 2-chloro-1-propene. Occupational exposure may occur through inhalation or dermal contact at workplaces where 2-chloro-1-propene is produced or used. (SRC)

Excerpt from ERG Guide 130P [Flammable Liquids (Water-Immiscible / Noxious)]: May cause toxic effects if inhaled or absorbed through skin. Inhalation or contact with material may irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution. (ERG, 2016)

Excerpt from ERG Guide 130P [Flammable Liquids (Water-Immiscible / Noxious)]: Ensure that medical personnel are aware of the material(s) involved and take precautions to protect themselves. Move victim to fresh air. Call 911 or emergency medical service. Give artificial respiration if victim is not breathing. Administer oxygen if breathing is difficult. Remove and isolate contaminated clothing and shoes. In case of contact with substance, immediately flush skin or eyes with running water for at least 20 minutes. Wash skin with soap and water. In case of burns, immediately cool affected skin for as long as possible with cold water. Do not remove clothing if adhering to skin. Keep victim calm and warm. Effects of exposure (inhalation, ingestion or skin contact) to substance may be delayed. (ERG, 2016)

SYMPTOMATOLOGY: 1. A. INHALATION, HIGH VAPOR CONCN: GASPING, REFUSAL TO BREATHE, COUGHING, SUBSTERNAL PAIN, & EXTREME RESP DISTRESS @ ... CONCN OVER 1500 PPM. IRRITATION OF EYES & UPPER RESP MUCOSA APPEARS PROMPTLY AFTER EXPOSURE TO CONCENTRATED VAPORS. LACRIMATION AND HEADACHE ARE PROMINENT. COMA MAY OCCUR RAPIDLY. B. INHALATION, LOW VAPOR CONCN: CENTRAL NERVOUS DEPRESSION & MODERATE IRRITATION OF RESP SYSTEM. 2. DERMAL: SEVERE SKIN IRRITATION WITH MARKED INFLAMMATORY RESPONSE OF EPIDERMIS & UNDERLYING TISSUES. /DICHLOROPROPENES/|SYMPTOMATOLOGY: 3. ORAL: ACUTE GI DISTRESS WITH PULMONARY CONGESTION & EDEMA. CNS DEPRESSION, PERHAPS EVEN IN ABSENCE OF IMPAIRED OXYGEN UPTAKE. 4. BY ANY ROUTE, POSSIBLE INJURIES TO LIVER, KIDNEYS & HEART. /DICHLOROPROPENES/

GRADE: 95% PURITY.

All other basic organic chemical manufacturing|1-Propene, 2-chloro-: ACTIVE|2-Chloro-1-propene is produced in small amounts during the production of allyl chloride from propylene.|2-Chloro-1-propene is formed during the cracking of 1,2-dichloropropane during allyl chloride production.

Fire Hazards -> Flammable - 4th degree, Reactive - 1st degree