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Serotonin hydrochloride

Serotonin hydrochloride structure

Serotonin hydrochloride 

structure
  • CAS No:

    153-98-0

  • Formula:

    C10H12N2O.ClH

  • Chemical Name:

    Serotonin hydrochloride

  • Synonyms:

    1H-Indol-5-ol,3-(2-aminoethyl)-,hydrochloride (1:1);Indol-5-ol,3-(2-aminoethyl)-,monohydrochloride;1H-Indol-5-ol,3-(2-aminoethyl)-,monohydrochloride;Hippophaine hydrochloride;Serotonin hydrochloride;5-Hydroxytryptamine hydrochloride;5-HT•HCl

  • Categories:

    Water Treatment Chemical  >  Water Stabilizer

Description

Serotonin hydrochloride is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin hydrochloride is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM.

Serotonin hydrochloride Basic Attributes

212.68

212.071640

3570963

244-464-4

GKN429M9VS

DTXSID80165186

29339900

Characteristics

62.04000

2.87700

white to off-white powder

167-168 °C

416.1ºC at 760 mmHg

205.4ºC

H2O: soluble

2-8°C

1.63E-07mmHg at 25°C

127.9 Ų [M+H-H2O]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Safety Information

III

6.1

UN2811

3

20/21/22-36/37/38

22-26-36

NM2571000

Xn,Xi,Hazard

Stable, but light sensitive and hygroscopic. Incompatible with strong oxidizing agents.

P261-P280-P305 + P351 + P338

H302-H312-H315-H319-H332-H335

|Danger|H301 (13.04%): Toxic if swallowed [Danger Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P310, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 46 companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Serotonin hydrochloride Use and Manufacturing

Serotonin is a monoamine neurotransmitter that is biochemically derived from tryptophan and produced in serotonergic neurons in the central nervous system and in enterochromaffin cells in the gastrointestinal tract. Serotonin is important in the regulation of mood, sleep, vomiting, sexuality, and appetite. Low levels of serotonin are associated with several disorders, including depression, migraines, bipolar disorder, and anxiety. Its actions are terminated primarily via uptake of serotonin from the synapse. Serotonin reuptake can be inhibited with MDMA, cocaine, tricyclic antidepressants, and selective serotonin reuptake inhibitors.[Cayman Chemical]

Computed Properties

Molecular Weight:212.67
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:212.0716407
Monoisotopic Mass:212.0716407
Topological Polar Surface Area:62
Heavy Atom Count:14
Complexity:174
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Drug Function and Efficacy

Serotonin is a neurotransmitter regulating mood, sleep, appetite, and anxiety

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Recommended Suppliers of Serotonin hydrochloride

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