Serotonin hydrochloride
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Serotonin hydrochloride
structure -
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CAS No:
153-98-0
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Formula:
C10H12N2O.ClH
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Chemical Name:
Serotonin hydrochloride
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Synonyms:
1H-Indol-5-ol,3-(2-aminoethyl)-,hydrochloride (1:1);Indol-5-ol,3-(2-aminoethyl)-,monohydrochloride;1H-Indol-5-ol,3-(2-aminoethyl)-,monohydrochloride;Hippophaine hydrochloride;Serotonin hydrochloride;5-Hydroxytryptamine hydrochloride;5-HT•HCl
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CAS No:
Description
Serotonin hydrochloride is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin hydrochloride is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM.
Serotonin hydrochloride Basic Attributes
212.68
212.071640
3570963
244-464-4
GKN429M9VS
DTXSID80165186
29339900
Characteristics
62.04000
2.87700
white to off-white powder
167-168 °C
416.1ºC at 760 mmHg
205.4ºC
H2O: soluble
2-8°C
1.63E-07mmHg at 25°C
127.9 Ų [M+H-H2O]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Safety Information
III
6.1
UN2811
3
20/21/22-36/37/38
22-26-36
NM2571000
Xn,Xi,Hazard
Stable, but light sensitive and hygroscopic. Incompatible with strong oxidizing agents.
P261-P280-P305 + P351 + P338
H302-H312-H315-H319-H332-H335
|Danger|H301 (13.04%): Toxic if swallowed [Danger Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P310, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 46 companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Serotonin hydrochloride Use and Manufacturing
Serotonin is a monoamine neurotransmitter that is biochemically derived from tryptophan and produced in serotonergic neurons in the central nervous system and in enterochromaffin cells in the gastrointestinal tract. Serotonin is important in the regulation of mood, sleep, vomiting, sexuality, and appetite. Low levels of serotonin are associated with several disorders, including depression, migraines, bipolar disorder, and anxiety. Its actions are terminated primarily via uptake of serotonin from the synapse. Serotonin reuptake can be inhibited with MDMA, cocaine, tricyclic antidepressants, and selective serotonin reuptake inhibitors.[Cayman Chemical]
Computed Properties
Molecular Weight:212.67
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:212.0716407
Monoisotopic Mass:212.0716407
Topological Polar Surface Area:62
Heavy Atom Count:14
Complexity:174
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
Drug Function and Efficacy
Serotonin is a neurotransmitter regulating mood, sleep, appetite, and anxiety
Recommended Suppliers of Serotonin hydrochloride
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CN
3 YRS
Business licensedTrader Supplier of Apigenin,PQQ,NMNHInquiryUnit Price: $10-11 /G FOBCAS No.: 153-98-0Grade: Chemical GradeContent: 99%
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