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Diafen

Diafen structure

CAS No:
132-18-3
Formula:
C19H23NO.ClH
Chemical Name:
Diafen
Synonyms:
Piperidine,4-(diphenylmethoxy)-1-methyl-,hydrochloride (1:1);Piperidine,4-(diphenylmethoxy)-1-methyl-,hydrochloride;Diafen hydrochloride;4-Diphenylmethoxy-1-methylpiperidine hydrochloride;Diphenylpyraline hydrochloride;Hispril hydrochloride;1-Methyl-4-piperidyl benzhydryl ether hydrochloride;Sumadil;Diphenpyraline hydrochloride;Diafen (antihistamine);Diafen;Diaphen;Lergoban;Dayfen;Belfene;Histryl;Kolton Jelly;Anginosan;Histryl Spansule Capsules;Lergobine;Hispril;Histyn;Diphenylpyraline teoclate
Categories:
Specialty Chemicals

Description

Diphenylpyraline Hcl is a first-generation antihistamine with anticholinergic effects, acts as a dopamine reuptake inhibitor, shows to be useful in the treatment of Parkinsonism.

Diafen Basic Attributes

Molecular Weight：

317.85300

Exact Mass：

317.15500

EC Number：

205-049-3

UNII：

G9FU7F1E87

NSC Number：

756730|61825

DSSTox ID：

DTXSID7047772

HScode：

2933399090

Characteristics

PSA：

12.47000

XLogP3：

4.62670

Melting Point：

206 °C

Boiling Point：

378.7ºC at 760mmHg

Flash Point：

111.6ºC

Water Solubility：

>47.7 [ug/mL]

Vapor Pressure：

6.18E-06mmHg at 25°C

Collision Cross Section：

173.8 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Safety Information

Packing level：

III

Hazard category：

6.1(b)

Transport codes：

UN 3249

hazard class code：

R20/21/22;R36/37/38

RTECS Number：

TM7823600

Marks：

Xn: Harmful;

Precautionary statement(s)：

P264, P270, P301+P312, P330, P501

Hazard Statements：

H302

GHS Classification：

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|Aggregated GHS information provided by 40 companies from 2 notifications to the ECHA C&L Inventory.

Drug Information

MeSH Entry Terms：

4-diphenylmethoxy-1-methylpiperidine

Diafen Use and Manufacturing

Manufacturing Info：

Piperidine, 4-(diphenylmethoxy)-1-methyl-, hydrochloride (1:1): INACTIVE

Use Classification：

Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients

Computed Properties

Molecular Weight:317.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:317.1546421
Monoisotopic Mass:317.1546421
Topological Polar Surface Area:12.5
Heavy Atom Count:22
Complexity:268
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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Diphenylpyraline hydrochloride

CAS No.: 132-18-3

Content: 99.00%

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