Lauryl methacrylate

254.41

254.41

205-570-6

B6L83074BZ

5188

DTXSID4027103

29161490

26.3

7.2

Clear light yellow Liquid

0.868 g/cm³ @ Temp: 20 °C

-20 °C

142 °C @ Press: 4 Torr

>230 °F

n 20/D 1.445(lit.)

H2O: insoluble

0-6°C

0.0012 mm Hg @ 25 deg C /Estimated/

Peritoneal-rat LD50: 12000 mg/kg; peritoneal-mouse LD50: 25000 mg/kg

Flammable; spicy and irritating smoke is emitted from the fire

Henry's Law constant: 3.3X10-3 atm cu m/mol @ 25 °C /Estimated/

Hydroxyl radical reaction rate constant: 3.4X10-11 cu cm/molecule-sec @ 25 °C /Estimated/|This compound is always a mixture of alkylmethacrylates with varying chain length; molecular weight: 254.46; melting point: -20 °C; boiling point: 153 °C; vapor pressure: 6.7 hPa (5.0 mm Hg); density: 0.87 @ 20 °C; water solubility: 3 mg/l: log Kow: 6.6 (measured)

No rapid reaction with air. No rapid reaction with water.

Acrylates and Acrylic Acids

Polymerizable

DODECYL METHACRYLATE is an acrylate ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides. Tends to polymerize. Oxidizing and reducing agents may initiate polymerization. Reaction may also occur when heated (USCG, 1999).

Autoflammability: 296 °C

III

9

UN 3082 9/PG 3

2

36/37/38-50/53

26-28-60-61-28B

OZ4300000

Xi,N

Treasury is ventilated, low temperature and dry; stored and transported separately from oxidant

Stable under normal temperatures and pressures.

P273-P305 + P351 + P338-P391

H315-H319-H335-H410

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.

Behavior in Fire: Heat can induce polymerization with rapid release of energy. Sealed containers may rupture explosively. (USCG, 1999)

|Warning|H315: Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P391, P403+P233, P405, and P501|H315 (98.79%): Causes skin irritation [Warning Skin corrosion/irritation]|Aggregated GHS information provided by 1075 companies from 25 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]|P261, P271, P304+P340, P312, P403+P233, P405, and P501|Not Classified|H320: Causes eye irritation [Warning Serious eye damage/eye irritation]|P264, P305+P351+P338, and P337+P313

Fire Extinguishing Agents: Foam, CO 2 or dry chemical (USCG, 1999)

Wear self-contained positive pressure breathing apparatus and full protective clothing. (USCG, 1999)|Suitable protective clothing and self-contained respiratory protective apparatus should be available for use of those who may have to rescue persons overcome by fumes. /acrylic acid and derivatives/

Combustible

... Hazard is the generation of considerable exothermic heat in some of the reactions, so that high pressures & temp may develop. This danger ... should be borne in mind when designing plant. Awareness of the dangers and of good engineering design are essential to safety. Employees should be instructed about the necessity of cleansing the skin if it is contaminated by materials which are irritants or skin-absorbed. With careful design, however, and complete enclosure of those processes where toxic chemicals or intermediates occur, dangerous exposures can be avoided. /Acrylic acid & derivatives/|SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.|SRP: Contaminated protective clothing should be segregated in such a manner so that there is no direct personal contact by personnel who handle, dispose, or clean the clothing. Quality assurance to ascertain the completeness of the cleaning procedures should be implemented before the decontaminated protective clothing is returned for reuse by the workers. Contaminated clothing should not be taken home at end of shift, but should remain at employee's place of work for cleaning.

practically nontoxic

LD50 Rat oral >5.0 g/kg|LD50 Rabbit percutaneous >3.0 g/kg|LD50 Rat ip 21.6 g/kg|LD50 Mouse oral >87,250 mg/kg|For more Non-Human Toxicity Values (Complete) data for N-DODECYL METHACRYLATE (6 total), please visit the HSDB record page.

Small quantities of methacrylates may readily be metabolized by saponification into the alcohol and methacrylic acid. The latter may form an acetyl-coenzyme A derivative, which then enters the normal lipid metabolism. /Methacrylates/|Acrylates and methacrylates are detoxified predominantly via conjugation with glutathione via the Michael addition reaction or glutathione-S-transferase. They are also likely to be hydrolyzed via carboxylesterases. The lower molecular weight esters are rapidly metabolized and eliminated, therefore, will not likely cause cumulative toxicity. /Methacrylates/

Inhalation temporarily reduces blood pressure from 5 to 25%, increases respiratory rate, decreases heart rate, and causes some EKG changes. Liquid may cause irritation of eyes and skin. May be harmful if swallowed. (USCG, 1999)

INHALATION: Move victim to fresh air. If breathing has stopped, give artificial respiration. If breathing is difficult, give oxygen. EYES OR SKIN: Flush with running water for at least 15 min; hold eyelids open if neccessary. Wash skin with soap and water. INGESTION: If victim is conscious, have victim drink milk or water and induce vomiting. If victim is unconscious or having convulsions, do nothing except keep victim warm. (USCG, 1999)

Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if needed. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Cover skin burns with dry sterile dressings after decontamination ... . /Poison A and B/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in respiratory arrest. Positive pressure ventilation techniques with a bag valve mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start an IV with D5W /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Poison A and B/

DMA, methacrylate

The commercial material is a mixture, containing also lower and higher fatty derivatives.

Adhesive manufacturing|2-Propenoic acid, 2-methyl-, dodecyl ester: ACTIVE|Methyl methacrylate, and in general the methacrylic esters, polymerize much less readily than the corresponding ordinary acrylates. None the less, they are stabilized by adding hydroquinone or pyrogallol, particularly in the presence of metallic copper. /Methacrylates/

Thin-layer chromatography (TLC), polarography, and spectrometry are used for soln measurements. Methacrylates in air have been analyzed by TLC, polarography, and colrimetry. Polarography has been used for determination of any residual monomer in the polymer. ... /Methacrylic acid & derivatives/

Cosmetics -> Viscosity controlling