Trimellitic anhydride chloride

white crystalline solid

PelletsLargeCrystals

50g of trimellitic anhydride, and45mL of cyclohexane was added dimethylaminopyridine 0.05g4- reaction flask washeated to 90 ° C, Was slowly added dropwise 37.2g of thionyl chloride (TMA /SOCl 2 molar ratio of 1: 1.2), the reaction was refluxed for 6h, until no gasevolution, The reaction solution obtained at the end the reaction, the reactionsolution was -0.085MPa recovered by distillation at 90 ° C the remainingcyclohexane and excess thionyl chloride, And then by vacuum distillation(degree of vacuum of 750 mm Hg) collected 180 ~ 190 ° C fraction obtained in47.6 g of trimellitic anhydride acid chloride, cooled After it is a whitecrystalline solid, mp 67.5~ 68.8 ° C, HPLC chromatography 99.5percent, yield 86.9percent.200 g of trimellitic anhydride, 120 mL of ethyl acetate and 0.02 g of tri-n-butylphosphine were added to the reaction flask, and the temperature was raised to 80 ° C.156 g of thionyl chloride was slowly added dropwise, and the reaction was refluxed for 6 hours until no gas evolved, and the reaction was completed to obtain a reaction solution.The reaction solution was distilled at -0.085 MPa at 80 ° C to recover residual benzene and excess thionyl chloride, and then vacuum distilled through a thin film evaporator.The degree of vacuum was 660 mmHg and the temperature was 130 °C.Collect 180-190 ° C fractions, Obtained 150.6 g of trimellitic anhydride acid chloride, After cooling, it was a white solid crystal with a melting point of 68.1 ° C and an HPLC chromatographic content of 99.25percent.

Plasticizers

Molecular Weight:210.57
XLogP3:1.8
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:209.9719863
Monoisotopic Mass:209.9719863
Topological Polar Surface Area:60.4
Heavy Atom Count:14
Complexity:312
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes